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Editorial Board
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IFC
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| Suicide risk in schizophrenia |
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Schizophrenia — A predictor of suicide during the second half of life?
24 October 2011
Abstract: Background: Little is known about the suicide risk of older adults diagnosed with schizophrenia. The purpose of the study is to examine whether older adults diagnosed with schizophrenia have...
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Annette Erlangsen,
William W. Eaton,
Preben Bo Mortensen,
Yeates Conwell
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111-117
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| Brain imaging |
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Lower effective connectivity between amygdala and parietal regions in response to fearful faces in schizophrenia
24 October 2011
Abstract: Behavioral abnormalities related to processing negative emotions such as fear have been demonstrated in schizophrenia. The amygdala is strongly associated with fear processing, and alteratio...
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Prerona Mukherjee,
Heather C. Whalley,
James W. McKirdy,
Andrew M. McIntosh,
Eve C. Johnstone,
Stephen M. Lawrie,
Jeremy Hall
et al.
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118-124
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Asymmetry of lexico-semantic processing in schizophrenia changes with disease progression
05 December 2011
Abstract: Background: Are anomalies of cerebral asymmetry integral to the disease process? Here, we examined the influence of age, chronicity and age of onset of illness in 34 patients with early onse...
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M. Lam,
S.L. Collinson,
K. Sim,
C.E. Mackay,
A.C.D. James,
T.J. Crow
et al.
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125-130
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Diminished language lateralization in schizophrenia corresponds to impaired inter-hemispheric functional connectivity
24 November 2011
Abstract: Introduction: A consistent brain imaging finding in schizophrenia is decreased language-asymmetry, already evident in first episode patients, thus arguing for a biomarker of the disorder. No...
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Maya Bleich-Cohen,
Haggai Sharon,
Ronit Weizman,
Michael Poyurovsky,
Sarit Faragian,
Talma Hendler
et al.
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131-136
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Effects of aging on the morphologies of Heschl's gyrus and the superior temporal gyrus in schizophrenia: A postmortem study
24 November 2011
Abstract: The etiology of schizophrenia has been proposed to be neurodevelopmental based on neuroimaging and molecular biological studies. If there is neuronal vulnerability based on neurodevelopment ...
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Youta Torii,
Shuji Iritani,
Hirotaka Sekiguchi,
Chikako Habuchi,
Minako Hagikura,
Tetsuaki Arai,
Kenji Ikeda,
Haruhiko Akiyama,
Norio Ozaki
et al.
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137-142
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Facial emotion processing in patients with schizophrenia and their non-psychotic siblings: A functional magnetic resonance imaging study
23 November 2011
Abstract: Background: Previous studies have shown that patients with schizophrenia show abnormalities in brain activation when processing emotional faces. However, very few studies have examined if su...
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Hui-jie Li,
Raymond C.K. Chan,
Qi-yong Gong,
Yu Liu,
Shan-ming Liu,
David Shum,
Zhen-ling Ma
et al.
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143-150
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Reduced striatal activation during reward anticipation due to appetite-provoking cues in chronic schizophrenia: A fMRI study
30 December 2011
Abstract: The occurrence of weight gain in schizophrenia (SZ) has profound clinical impact and interacts with antipsychotic medication, life style and disease severity. The functional neuroanatomy und...
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O. Grimm,
S. Vollstädt-Klein,
L. Krebs,
M. Zink,
M.N. Smolka
et al.
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151-157
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Mentalizing impairment in schizophrenia: A functional MRI study
23 September 2011
Abstract: Background: A deficit in Theory of mind (ToM) or ‘mentalizing’ has been purported to underlie the poor social functioning seen in patients with schizophrenia. To understand the neural basis ...
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Pritha Das,
Jim Lagopoulos,
Carissa M. Coulston,
Antony F. Henderson,
Gin S. Malhi
et al.
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158-164
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An MRI study of septi pellucidi in relation to hippocampus volume and fornix integrity in schizophrenia
19 December 2011
Abstract: Septum pellucidum (SP) and cavum SP (CSP) were delineated in two samples. The Longitudinal Study examined structural MR-images in first-episode schizophrenia (FESZ) and controls at two time-...
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Charlie A. Davidson,
Noriomi Kuroki,
Jorge L. Alvarado,
Margaret A. Niznikiewicz,
Robert W. McCarley,
James J. Levitt
et al.
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165-170
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Decreased activity in right-hemisphere structures involved in social cognition in siblings discordant for schizophrenia
05 December 2011
Abstract: Background: Social cognitive deficits contribute to functional disability in schizophrenia. Social cognitive tasks in healthy persons consistently evoke activation of medial prefrontal corte...
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Delfina de Achával,
Mirta F. Villarreal,
Elsa Y. Costanzo,
Jazmín Douer,
Mariana N. Castro,
Martina C. Mora,
Charles B. Nemeroff,
Elvina Chu,
Karl-Jürgen Bär,
Salvador M. Guinjoan
et al.
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171-179
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| Treatment |
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When can patients with potentially life-threatening adverse effects be rechallenged with clozapine? A systematic review of the published literature
23 November 2011
Abstract: Background: Clozapine is widely prescribed for treatment refractory patients with schizophrenia, but its use is limited by potentially life threatening adverse effects. Rechallenge after the...
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Peter Manu,
Deepak Sarpal,
Owen Muir,
John M. Kane,
Christoph U. Correll
et al.
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180-186
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Does long-acting injectable risperidone make a difference to the real-life treatment of schizophrenia? Results of the Cohort for the General study of Schizophrenia (CGS)
02 December 2011
Abstract: Objective: The primary aim of this study was to compare the impact of risperidone long-acting injectable (R-LAI) to other antipsychotics on rates of hospitalisation in real-life settings. Me...
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Lamiae Grimaldi-Bensouda,
Frederic Rouillon,
Bernard Astruc,
Michel Rossignol,
Jacques Benichou,
Bruno Falissard,
Frederic Limosin,
Beatrice Beaufils,
Guillaume Vaiva,
Helene Verdoux,
Yola Moride,
Alban Fabre,
Florence Thibaut,
Lucien Abenhaim,
for the CGS Study Group
et al.
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187-194
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Responses to antipsychotic therapy among patients with schizophrenia or schizoaffective disorder and either predominant or prominent negative symptoms
24 October 2011
Abstract: Patients with schizophrenia who have predominant negative symptoms are often considered less responsive to treatment. This analysis of patients with schizophrenia or schizoaffective disorder...
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Virginia L. Stauffer,
Guochen Song,
Bruce J. Kinon,
Haya Ascher-Svanum,
Lei Chen,
Peter D. Feldman,
Robert R. Conley
et al.
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195-201
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Alpha-2 receptor antagonist add-on therapy in the treatment of schizophrenia; a meta-analysis
15 December 2011
Abstract: Introduction: Reduced dopaminergic activity in the pre-frontal cortex may partially explain the negative symptoms of schizophrenia. Animal models have shown that adding an alpha-2 adrenergic...
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Eric Michael Hecht,
David C. Landy
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202-206
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Rimonabant for neurocognition in schizophrenia: A 16-week double blind randomized placebo controlled trial
05 December 2011
Abstract: Objective: To examine the effect of rimonabant on neurocognitive impairments in people with schizophrenia. Methods: Participants entered a 16-week double-blind, placebo-controlled, randomize...
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Douglas L. Boggs,
Deanna L. Kelly,
Robert P. McMahon,
James M. Gold,
David A. Gorelick,
Jared Linthicum,
Robert R. Conley,
Fang Liu,
James Waltz,
Marilyn A. Huestis,
Robert W. Buchanan
et al.
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207-210
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Comparative gene expression study of the chronic exposure to clozapine and haloperidol in rat frontal cortex
12 December 2011
Abstract: Antipsychotic drugs (APDs) are effective in treating some of the positive and negative symptoms of schizophrenia. APDs take time to achieve a therapeutic effect which suggests that changes i...
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S. Hossein Fatemi,
Timothy D. Folsom,
Teri J. Reutiman,
Jessica Novak,
Rachelanne H. Engel
et al.
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211-218
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Antipsychotic treatment for schizophrenia in the maintenance phase: A systematic review of the guidelines and algorithms
12 December 2011
Abstract: Objective: Antipsychotic treatment strategy for the maintenance phase of schizophrenia has been inconsistent in the literature. The purpose of this systematic review is to overview recommend...
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Hiroyoshi Takeuchi,
Takefumi Suzuki,
Hiroyuki Uchida,
Koichiro Watanabe,
Masaru Mimura
et al.
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219-225
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Symptom severity and attitudes toward medication: Impacts on adherence in outpatients with schizophrenia
02 December 2011
Abstract: Objective: The primary aim of this study was to compare electronic monitoring with other measures of adherence to antipsychotic medication in outpatients with schizophrenia. The secondary ai...
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Jaewon Yang,
Young-Hoon Ko,
Jong-Woo Paik,
Moon-Soo Lee,
Changsu Han,
Sook-Haeng Joe,
In-Kwa Jung,
Hyun-Gang Jung,
Seung-Hyun Kim
et al.
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226-231
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Sensorimotor gating and clinical outcome following cognitive behaviour therapy for psychosis
05 December 2011
Abstract: Background: Prepulse inhibition (PPI) of the startle response refers to the ability of a weak prestimulus to transiently inhibit the response to a closely following strong sensory stimulus. ...
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Veena Kumari,
Preethi Premkumar,
Dominic Fannon,
Ingrid Aasen,
Satya Raghuvanshi,
Anantha P. Anilkumar,
Elena Antonova,
Emmanuelle R. Peters,
Elizabeth Kuipers
et al.
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232-238
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| Genetics |
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Genetic and functional analysis of the gene encoding GAP-43 in schizophrenia
05 December 2011
Abstract: Objectives: In earlier reports, growth-associated protein 43 (GAP-43) has been shown to be critical for initial establishment or reorganization of synaptic connections, a process thought to ...
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Yu-Chih Shen,
Ho-Min Tsai,
Min-Chih Cheng,
Shih-Hsin Hsu,
Shih-Fen Chen,
Chia-Hsiang Chen
et al.
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239-245
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Modelling the contribution of family history and variation in single nucleotide polymorphisms to risk of schizophrenia: A Danish national birth cohort-based study
23 November 2011
Abstract: Background: Epidemiological studies indicate that having any family member with schizophrenia increases the risk of schizophrenia in the probands. However, genome-wide association studies (G...
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Esben Agerbo,
Preben B. Mortensen,
Carsten Wiuf,
Michael S. Pedersen,
John McGrath,
Mads V. Hollegaard,
Bent Nørgaard-Pedersen,
David M. Hougaard,
Ole Mors,
Carsten B. Pedersen
et al.
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246-252
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Hippocampal volume and the brain-derived neurotrophic factor Val66Met polymorphism in first episode psychosis
23 December 2011
Abstract: Introduction: Small hippocampi and impaired memory are common in patients with psychosis and brain-derived neurotrophic factor (BDNF) plays a critical role in hippocampal neuroplasticity and...
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Geoffrey N. Smith,
Allen E. Thornton,
Donna J. Lang,
G. William MacEwan,
Thomas S. Ehmann,
Lili C. Kopala,
Karen Tee,
Gillian Shiau,
Aristotle N. Voineskos,
James L. Kennedy,
William G. Honer
et al.
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253-259
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Epigenetic regulation on GABRB2 isoforms expression: Developmental variations and disruptions in psychotic disorders
29 December 2011
Abstract: Introduction: To improve the understanding of psychotic abnormalities and their non-Mendelian inheritance patterns, the epigenetic regulation of the psychotic disorder-associated GABRB2, gen...
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Cunyou Zhao,
Feng Wang,
Frank W. Pun,
Lingling Mei,
Lihuan Ren,
Zhiliang Yu,
Siu-Kin Ng,
Jianhuan Chen,
Shui-Ying Tsang,
Hong Xue
et al.
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260-266
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| Psychometrics |
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Psychometric properties and validity of short forms of the Wisconsin Schizotypy Scales in two large samples
21 December 2011
Abstract: The Wisconsin Schizotypy Scales (WSS) have been widely used in the study of clinical and non-clinical samples. However, researchers often find the length of the scales prohibitive. The prese...
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Georgina M. Gross,
Paul J. Silvia,
Neus Barrantes-Vidal,
Thomas R. Kwapil
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267-272
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Brief Psychiatric Rating Scale — Excited Component (BPRS-EC) and neuropsychological dysfunction predict aggression, suicidality, and involuntary treatment in first-episode psychosis
05 January 2012
Abstract: Objective: Aggression, suicidality and involuntary treatment constitute severe clinical problems in first-episode psychosis (FEP). Although there are studies on prevalence and clinical predi...
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Christian G. Huber,
Daniel Schöttle,
Martin Lambert,
Birgit Hottenrott,
Agorastos Agorastos,
Dieter Naber,
Katrin Schroeder
et al.
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273-278
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The MATRICS Consensus Cognitive Battery (MCCB): Co-norming and standardization in Spain
22 December 2011
Abstract: The MATRICS Consensus Cognitive Battery (MCCB), developed by the National Institute of Mental Health (NIMH) Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS)...
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R. Rodriguez-Jimenez,
A. Bagney,
C. Garcia-Navarro,
A.I. Aparicio,
R. Lopez-Anton,
M. Moreno-Ortega,
M.A. Jimenez-Arriero,
J.L. Santos,
A. Lobo,
R.S. Kern,
M.F. Green,
K.H. Nuechterlein,
T. Palomo
et al.
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279-284
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| Letters to the Editor |
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Magnetic resonance perfusion imaging of auditory verbal hallucinations in patients with schizophrenia
19 December 2011
Auditory verbal hallucinations (AVH) are a core symptom of schizophrenia and related spectrum-disorders. So far, magnetic resonance imaging (MRI) has been employed to study the functional neuroanatomy...
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Nadine Donata Wolf,
Georg Grön,
Fabio Sambataro,
Nenad Vasic,
Karel Frasch,
Markus Schmid,
Philipp Arthur Thomann,
Robert Christian Wolf
et al.
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285-287
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Admixture analysis of Age at Onset in Schizophrenia: Genetic Association Study of 45 candidate loci
22 December 2011
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Vincenzo De Luca,
Clement Zai,
Renan de Souza,
Gina Polsinelli,
Celine Teo,
Takahiro Shinkai,
Albert Wong,
Bernard Le Foll,
James L. Kennedy
et al.
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288-290
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Neuronal deficit in medial pulvinar from right but not left hemisphere in schizophrenia
14 November 2011
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Maxwell I. Mileaf,
William Byne
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291-292
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Comment on Milanovic et al.
24 October 2011
We read the study published in Schizophrenia Research with great interest. In their fMRI study comparing cerebral activation in the dorsolateral prefrontal cortex (DLPC) and medial prefrontal cortex ...
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Olivier Maïza,
Sonia Dollfus
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293
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Medial prefrontal cortical activation during working memory differentiates schizophrenia and bipolar psychotic patients: A pilot fMRI study: Response to the comment
09 November 2011
We would like to thank , for their comments on our findings of differential medial prefrontal cortical (mPFC) signals across task runs in persons with schizophrenia (SZ). We hypothesized that the diff...
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Snezana M. Milanovic,
Mark G. Vangel
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294-295
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31P-MR spectroscopy in monozygotic twins discordant for schizophrenia or schizoaffective disorder
04 November 2011
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Igor Nenadic,
Kerstin Langbein,
Matthias Weisbrod,
Raka Maitra,
Reinhard Rzanny,
Alexander Gussew,
Jürgen R. Reichenbach,
Heinrich Sauer,
Stefan Smesny
et al.
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296-297
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Qualitative content of auditory hallucinations and suicidal behavior in schizophrenia
23 September 2011
Whereas depressed mood, hopelessness, and previous suicide attempts have been well established as risk factors for suicidal behavior in schizophrenia (), the role of psychotic symptoms and their quali...
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Samuel G. Siris,
Francisco J. Acosta
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298-299
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Early network alterations in the subiculum of offspring following gestational maternal immune activation
26 December 2011
In the hippocampus of schizophrenia, important dysfunctions in glutamatergic and GABAergic synaptic transmission () are commonly found suggesting that the delicate balance between excitation and inhib...
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Germaine C. Lowe,
Romain Goutagny,
Guillaume Ducharme,
Jesse Jackson,
Sylvain Williams
et al.
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300-301
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Intermittent aripiprazole for schizophrenia
03 January 2012
Medication nonadherence is associated with poorer outcome in schizophrenia. A 1–10day gap in taking medication is associated with a 2-fold increase in risk of hospitalization (). As the gap increases ...
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Kathryn Brotzge,
Manoochehr Manshadi,
Rif S. El-Mallakh
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302-303
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| Corrigendum |
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Corrigendum to "Trajectories of response to treatment with atypical antipsychotic medication in patients with schizophrenia pooled from 6 double-blind, randomized clinical trials" [Shizophr. Res. 130 (2011) 11–19]
We would like to correct an error regarding the affiliation and disclosure of Shitij Kapur, MD, a co-author of the above paper that was published in the August 2011 issue of Schizophrenia Research. Dr...
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Virginia Stauffer,
Michael Case,
Sara Kollack-Walker,
Haya Ascher-Svanum,
Tamara Ball,
Shitij Kapur,
Bruce J. Kinon
et al.
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304
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