Schizophrenia Research
Volume 42, Issue 1 , Pages 47-55 , 16 March 2000

The longitudinal relationship of clinical symptoms, cognitive functioning, and adaptive life in geriatric schizophrenia

  • Susan R McGurk

      Affiliations

    • Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    • Corresponding Author InformationCorresponding author. Present address: Pilgrim Psychiatric Center, Clinical Neuroscience Treatment Unit, Building 81/102, 998 Crooked Hill Road, West Brentwood, NY 11717, USA
    • ,
  • Patrick J Moriarty

      Affiliations

    • Department of Psychology, Hofstra University, Hempstead, NY 11550, USA
    • ,
  • Philip D Harvey

      Affiliations

    • Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    • ,
  • Michael Parrella

      Affiliations

    • Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    • Pilgrim Psychiatric Center, Clinical Neuroscience Treatment Unit, Building 81/102, 998 Crooked Hill Road, West Brentwood, NY 11717, USA
    • ,
  • Leonard White

      Affiliations

    • Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    • Pilgrim Psychiatric Center, Clinical Neuroscience Treatment Unit, Building 81/102, 998 Crooked Hill Road, West Brentwood, NY 11717, USA
    • ,
  • Kenneth L Davis

      Affiliations

    • Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA

Received 19 January 1999 ,Accepted 20 May 1999.

References 

  1. Corrigan PW, Wallace CJ, Schade MI, Green MF. Cognitive dysfunctions and psychosocial skill learning in schizophrenia. Beh. Ther. 1994;25:5–15
  2. Davidson M, Harvey PD, Powchik P, Parrella M, White L, Knobler HY, et al. Severity of symptoms in geriatric chronic schizophrenic patients. Am. J. Psychiatry. 1995;152:197–207
  3. Davidson M, Harvey PD, Welsh KA, Powchik P, Putnam KM, Mohs RC. Characterization of the cognitive impairment of old-age schizophrenia: A comparison to patients with Alzheimer's disease. Am. J. Psychiatry. 1996;153:1274–1279
  4. Green MF. What are the functional consequences of neurocognitive deficits in schizophrenia?. Am. J. Psychiatry. 1996;153:321–330
  5. Harvey PD, Davidson M, Mueser KT, Parrella M, White L. The Social Adaptive Functioning Evaluation: An assessment measure for geriatric psychiatric patients. Schizophr. Bull. 1997;23:131–146
  6. Harvey PD, Powchik P, Parrella M, White L, Davidson M. Symptom severity and cognitive impairment in chronically hospitalized geriatric patients with mood disorders. Br. J. Psychiatry. 1997;170:369–374
  7. Harvey PD, Sukhodolsky D, Parrella M, White L, Davidson M. The association between adaptive and cognitive deficits in geriatric chronic schizophrenic patients. Schizophr. Res. 1997;27:211–218
  8. Harvey PD, Howanitz E, Parrella M, White L, Hoblyn J, Mohs RC, et al. Cognitive adaptive and clinical symptoms in geriatric patients with lifelong schizophrenia: A comparative study across treatment sites. Am. J. Psychiatry. 1998;155:1080–1086
  9. Harvey PD, Lombardi J, Leibman M, White L, Parrella M, Powchik P, et al. Cognitive impairment and negative symptoms in schizophrenia: A prospective study of their relationship. Schizophr. Res. 1996;22:223–231
  10. Harvey PD, Parrella M, White L, Mohs RC, Davis KL. The convergence of cognitive and adaptive decline in late-life schizophrenia. Schizophr. Res. 1999;in press
  11. Harvey PD, Silverman J, Mohs RC, Powchik P, Davidson M, Davis KL. Cognitive functioning in late-life schizophrenia: A prospective study of cognitive decline. Biol. Psychiatry. 1999;in press
  12. Jaeger J, Douglas E. Neuropsychiatric rehabilitation for persistent mental illness. Psychiat. Quart. 1992;63:71–93
  13. Lezak MD. Neuropsychological Assessment. 3rd ed.. Oxford: Oxford Univ. Press; 1995;
  14. Lysaker P, Bell M, Beam-Goulet J. Wisconsin Card Sorting Test and work performance in schizophrenia. Psychiatr. Res. 1995;56:45–51
  15. Meltzer HY, McGurk SR. The effects of clozapine risperidone and olanzapine on cognitive functioning in schizophrenia. Schizophr. Bull. 1999;in press
  16. Mueser KT, Bellack AS, Douglas MS, Wade JH. Prediction of social skills acquisition in schizophrenic and major affective disorder patients from memory and symptomotology. Psychiatr. Res. 1991;37:281–296
  17. Perlick D, Mattis S, Stastny P, Teresi J. Neuropsychological discriminators of long-term inpatient or outpatient status in chronic schizophrenia. J. Neuropsychiatr. Clin. Neurosci. 1992;4:428–434
  18. Velligan DI, Mahurin RK, Diamond PL, Hazleton BC, Eckert SL, Miller AL. The functional significance of symptomotology and cognitive function in schizophrenia. Schizophr. Res. 1997;25:21–31

PII: S0920-9964(99)00097-3

Schizophrenia Research
Volume 42, Issue 1 , Pages 47-55 , 16 March 2000

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