Schizophrenia Research
Volume 41, Issue 3 , Pages 397-403 , 14 February 2000

A magnetic resonance imaging study of corpus callosum size in familial schizophrenic subjects,their relatives, and normal controls

  • S.E. Chua

      Affiliations

    • Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    • Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, PR China
    • Corresponding Author InformationCorresponding author. Tel.: +852-28554486; fax: +852-28551345
    • ,
  • T. Sharma

      Affiliations

    • Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    • ,
  • N. Takei

      Affiliations

    • Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    • ,
  • R.M. Murray

      Affiliations

    • Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    • ,
  • P.W.R. Woodruff

      Affiliations

    • Neuroscience and Psychiatry Unit, Stopford Building, The University of Manchester, Oxford Road, Manchester M13 9PT, United Kingdom

References 

  1. American Psychiatric Association, Committee on Nomenclature and Statistics. In: Diagnostic and Statistical Manual of Mental Disorders. Revised 3rd edition. Washington, DC: American Psychiatric Association; 1987;
  2. Barta PE, Dhingra L, Royall R, et al.  Improving stereological estimates for the volume of structures identified in three-dimensional arrays of spatial data. J. Neurosci. Meth. 1997;75:111–118
  3. Casanova MF, Sanders RD, Goldberg TE, et al.  Morphometry of the corpus callosum in monozygotic twins discordant for schizophrenia : a magnetic resonance imaging study. J. Neurol. Neurosurg. Psychiatry. 1990;53:416–421
  4. De Lacoste-Utamsing C, Holloway RL. Sexual dimorphism in the human corpus callosum. Science. 1982;216:1431–1432
  5. Endicott J, Andreasen NC, Spitzer RL. Family History Research Diagnostic Criteria. New York: New York State Psychiatric Insititute; 1975;
  6. Frangou S, Sharma T, Sigmundsson T, et al.  The Maudsley Family Study 4. Normal planum temporale asymmetry in familial schizophrenia. A volumetric MRI study. Br. J. Psychiatry. 1997;170:328–333
  7. Giedd JN, Rumsey JM, Castellanos X, et al.  A quantitative MRI study of the corpus callosum in children and adolescents. Dev. Brain Res. 1996;91:274–280
  8. Gottesman II, Shields J. A Twin Study Vantage Point. London: Academic Press; 1972;
  9. Office of Population Censuses and Surveys. Classification of Occupations. Standard Occupational Classification (SOC). London: HMSO; 1991;
  10. Rauch RA, Jinkins JR. Analysis of cross-sectional area measurements of the corpus callosum adjusted for brain size in male and female subjects from childhood to adulthood. Behav. Brain Res. 1994;64:65–78
  11. Reveley AM, Reveley MA, Clifford CA, et al.  Cerebral ventricular size in twins discordant for schizophrenia. The Lancet March 6. 1982;i:540–541
  12. Robb RA. A software system for interactive and quantitative analysis of biomedical images. In:  Hohne KH,  Fuchs H,  Pizer SM editor. 3D Imaging in Medicine. London: Springer-Verlag; 1990;p. 540–541
  13. Shenton ME, Kikinis R, Jolesz FA, et al.  Abnormalities of the left temporal lobe and thought disorder in schizophrenia. New Engl. J. Med. 1992;327:604–612
  14. Spitzer RL, Endicott J. Schedule for Affective Disorders and Schizophrenia — Lifetime Version. New York: New York State Psychiatric Insititute; 1978;
  15. Suddath RL, Christison GW, Torrey EF, et al.  Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia. New Engl. J. Med. 1990;322:789–794
  16. Witelson SF. The corpus callosum is larger in left-handers. Science. 1985;229:665–668
  17. Witelson SF. Hand and sex differences in the isthmus and genu of the human corpus callosum. Brain. 1989;112:799–833
  18. Woodruff PWR, Pearlson GD, Geer MJ, et al.  A computerized magnetic resonance imaging of corpus callosum morphology in schizophrenia. Psychol. Med. 1993;23:45–56
  19. Woodruff PWR, McManus IC, David AS. Meta-analysis of corpus callosum size in schizophrenia. J. Neurol. Neurosurg. Psychiatry. 1995;58:7–461
  20. Woodruff PWR, Philips ML, Rushe T, et al.  Corpus callosum size and inter-hemispheric function in schizophrenia. Schizophr. Res. 1997;23:189–196

PII: S0920-9964(99)00081-X

Schizophrenia Research
Volume 41, Issue 3 , Pages 397-403 , 14 February 2000

Article Tools

* Image Usage & Resolution