Letter to the EditorGabapentin prevents behavioral changes on the amphetamine-induced animal model of schizophrenia
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Influence of the dose of ketamine used on schizophrenia-like symptoms in mice: A correlation study with TH, GAD<inf>67</inf>, and PPAR-γ
2023, Pharmacology Biochemistry and BehaviorKava decreases the stereotyped behavior induced by amphetamine in mice
2021, Journal of EthnopharmacologyCitation Excerpt :Correct alternation was defined as successive entries into the three different arms, on overlapping triplet sets for example ABC, BCA, CAB. The percentage of alternation was calculated as total of alternations/(total arm entries − 2) x 100 (Ceretta et al., 2016; Dall’Igna et al., 2007; Monte et al., 2013). To carry out MAO activity ex vivo the brain structures were homogenized in assay buffer (16.8 mM Na2HPO4, 10.6 mM KH2PO4, 3.6 mM KCl, pH 7.4) and, the homogenate was used to determine the protein quantity as previously described Lowry (1951).
Gabapentin reduces haloperidol-induced vacuous chewing movements in mice
2018, Pharmacology Biochemistry and BehaviorCitation Excerpt :Furthermore, it has been reported that GBP decreases excitatory signals in the central nervous system by modulation of the α2δ calcium channel (Bayer et al., 2004; Fink et al., 2000; Sills, 2006). Our group recently demonstrated that GBP has a potential antipsychotic-like effect on behavioral parameters in an animal model of schizophrenia (Ceretta et al., 2016). However, there are no studies evaluating the effects of GBP on extrapyramidal symptoms resulting from conventional antipsychotic therapy.
Advantages and Limitations of Animal Schizophrenia Models
2022, International Journal of Molecular Sciences