Schizophrenia Research
Volume 134, Issue 1 , Pages 10-15 , January 2012

Reduced prepulse inhibition as an early vulnerability marker of the psychosis prodrome in adolescence

  • Tim B. Ziermans

      Affiliations

    • Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    • Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    • Corresponding Author InformationCorresponding author at: Department of Neuroscience, Retzius Väg 8, Karolinska Institutet, 171 77 Stockholm, Sweden. Tel.: +46 8 524 86 372.
    • ,
  • Patricia F. Schothorst

      Affiliations

    • Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    • ,
  • Mirjam Sprong

      Affiliations

    • Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    • ,
  • Maurice J.C.M. Magnée

      Affiliations

    • Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    • ,
  • Herman van Engeland

      Affiliations

    • Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    • ,
  • Chantal Kemner

      Affiliations

    • Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    • Department of Developmental Psychology, Faculty of Social Sciences, Utrecht University, The Netherlands

Received 18 January 2010 ,Revised 4 October 2011 ,Accepted 20 October 2011.

Title About Type File Size
APPLICATION

Supplementary material.

 Other 0 MB
APPLICATION

Table. Group means±standard deviations for P50 and prepulse inhibition (PPI) parameters.

 Other 0 MB
Figure 1

Smooth pursuit position gain (panels A and B) and number of saccades per stimulus velocity (panels C and D). Displayed seperately for all participants (panels A and C; 60 controls, 48 ultra-high risk individuals without psychosis [UHR-NP], 7 ultra-high risk individuals with psychosis [UHR-P]) and medication-naive participants (panels B and D; 60 controls, 30 UHR-NP, 5 UHR-P).

 Other 0 MB

Please note that add-on components may require plug-in applications.

PII: S0920-9964(11)00544-5

doi: 10.1016/j.schres.2011.10.009

Schizophrenia Research
Volume 134, Issue 1 , Pages 10-15 , January 2012

Article Tools

* Image Usage & Resolution