Schizophrenia Research
Volume 122, Issue 1 , Pages 24-30 , September 2010

The catechol-O-methyl transferase (COMT) gene and its potential association with schizophrenia: Findings from a large German case-control and family-based sample

  • Vanessa Nieratschker

      Affiliations

    • Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
    • ,
  • Josef Frank

      Affiliations

    • Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
    • ,
  • Thomas W. Mühleisen

      Affiliations

    • Department of Genomics, Life & Brain Center, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
    • Institute of Human Genetics, Biomedical Center, University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
    • ,
  • Jana Strohmaier

      Affiliations

    • Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
    • ,
  • Jens R. Wendland

      Affiliations

    • Unit on the Genetic Basis of Mood and Anxiety Disorders, NIMH, NIH, 35 Convent Drive, Bethesda, MD, USA
    • ,
  • Johannes Schumacher

      Affiliations

    • Department of Genomics, Life & Brain Center, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
    • Unit on the Genetic Basis of Mood and Anxiety Disorders, NIMH, NIH, 35 Convent Drive, Bethesda, MD, USA
    • ,
  • Jens Treutlein

      Affiliations

    • Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
    • ,
  • René Breuer

      Affiliations

    • Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
    • ,
  • Rami Abou Jamra

      Affiliations

    • Institute of Human Genetics, Biomedical Center, University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
    • Institute of Human Genetics, University of Erlangen, Schwabachanlage 10, 91054 Erlangen, Germany
    • ,
  • Manuel Mattheisen

      Affiliations

    • Department of Genomics, Life & Brain Center, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
    • Institute of Human Genetics, Biomedical Center, University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
    • Institute for Medical Biometry, Informatics, and Epidemiology (IMBIE), University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
    • ,
  • Stefan Herms

      Affiliations

    • Department of Genomics, Life & Brain Center, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
    • Institute of Human Genetics, Biomedical Center, University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
    • ,
  • Christine Schmäl

      Affiliations

    • Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
    • ,
  • Wolfgang Maier

      Affiliations

    • Department of Psychiatry and Psychotherapy, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
    • ,
  • Markus M. Nöthen

      Affiliations

    • Department of Genomics, Life & Brain Center, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
    • Institute of Human Genetics, Biomedical Center, University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
    • ,
  • Sven Cichon

      Affiliations

    • Department of Genomics, Life & Brain Center, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
    • Institute of Human Genetics, Biomedical Center, University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
    • Institute of Neurosciences and Medicine (INM-1), Research Center Juelich, Wilhelm-Johnen-Straße, 52428 Juelich, Germany
    • ,
  • Marcella Rietschel

      Affiliations

    • Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
    • ,
  • Thomas G. Schulze

      Affiliations

    • Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
    • Department of Psychiatry and Psychotherapy, University of Göttingen, von-Siebold-Straße 5, 37075 Göttingen, Germany
    • Corresponding Author InformationCorresponding author. Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, J5, 68159 Mannheim, Germany. Tel.: +49 621 1703 6052; fax: +49 621 1703 6055.

Received 13 January 2010 ,Revised 2 June 2010 ,Accepted 24 June 2010.

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PII: S0920-9964(10)01375-7

doi: 10.1016/j.schres.2010.06.018

Schizophrenia Research
Volume 122, Issue 1 , Pages 24-30 , September 2010

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