The catechol-O-methyl transferase (COMT) gene and its potential association with schizophrenia: Findings from a large German case-control and family-based sample

Nieratschker, Vanessa; Frank, Josef; Mühleisen, Thomas W.; Strohmaier, Jana; Wendland, Jens R.; Schumacher, Johannes; Treutlein, Jens; Breuer, René; Jamra, Rami Abou; Mattheisen, Manuel; Herms, Stefan; Schmäl, Christine; Maier, Wolfgang; Nöthen, Markus M.; Cichon, Sven; Rietschel, Marcella; Schulze, Thomas G.

doi:10.1016/j.schres.2010.06.018

« Previous Next »Schizophrenia Research
Volume 122, Issue 1 , Pages 24-30, September 2010

The catechol-O-methyl transferase (COMT) gene and its potential association with schizophrenia: Findings from a large German case-control and family-based sample

Vanessa Nieratschker
- Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
Josef Frank
- Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
Thomas W. Mühleisen
- Department of Genomics, Life & Brain Center, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
- Institute of Human Genetics, Biomedical Center, University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
Jana Strohmaier
- Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
Jens R. Wendland
- Unit on the Genetic Basis of Mood and Anxiety Disorders, NIMH, NIH, 35 Convent Drive, Bethesda, MD, USA
Johannes Schumacher
- Department of Genomics, Life & Brain Center, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
- Unit on the Genetic Basis of Mood and Anxiety Disorders, NIMH, NIH, 35 Convent Drive, Bethesda, MD, USA
Jens Treutlein
- Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
René Breuer
- Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
Rami Abou Jamra
- Institute of Human Genetics, Biomedical Center, University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
- Institute of Human Genetics, University of Erlangen, Schwabachanlage 10, 91054 Erlangen, Germany
Manuel Mattheisen
- Department of Genomics, Life & Brain Center, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
- Institute of Human Genetics, Biomedical Center, University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
- Institute for Medical Biometry, Informatics, and Epidemiology (IMBIE), University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
Stefan Herms
- Department of Genomics, Life & Brain Center, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
- Institute of Human Genetics, Biomedical Center, University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
Christine Schmäl
- Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
Wolfgang Maier
- Department of Psychiatry and Psychotherapy, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
Markus M. Nöthen
- Department of Genomics, Life & Brain Center, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
- Institute of Human Genetics, Biomedical Center, University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
Sven Cichon
- Department of Genomics, Life & Brain Center, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
- Institute of Human Genetics, Biomedical Center, University of Bonn, Sigmund-Freud-Str. 25, 53127, Germany
- Institute of Neurosciences and Medicine (INM-1), Research Center Juelich, Wilhelm-Johnen-Straße, 52428 Juelich, Germany
Marcella Rietschel
- Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
Thomas G. Schulze
- Department of Genetic Epidemiology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany
- Department of Psychiatry and Psychotherapy, University of Göttingen, von-Siebold-Straße 5, 37075 Göttingen, Germany
- Corresponding author. Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, J5, 68159 Mannheim, Germany. Tel.: +49 621 1703 6052; fax: +49 621 1703 6055.