Schizophrenia Research
Volume 120, Issue 1 , Pages 84-86 , July 2010

Asymmetry loss is local rather than global in adolescent onset schizophrenia

  • Gina M. Clark

      Affiliations

    • College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    • Department of Psychiatry, Oxford University, Oxford, UK
    • Department of Experimental Psychology, Oxford University, OX1 3UD, UK
    • ,
  • Timothy J. Crow

      Affiliations

    • Department of Psychiatry, Oxford University, Oxford, UK
    • Corresponding Author InformationCorresponding author. SANE Prince of Wales International Centre, Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK. Tel.: +44 1865 455917; fax: +44 1865 455922.
    • ,
  • Thomas R. Barrick

      Affiliations

    • MARIAC, University of Liverpool, Liverpool, L69 3GE, UK
    • ,
  • Simon L. Collinson

      Affiliations

    • Department of Psychiatry, Oxford University, Oxford, UK
    • National University of Singapore, Singapore
    • ,
  • Anthony C. James

      Affiliations

    • Department of Psychiatry, Oxford University, Oxford, UK
    • ,
  • Neil Roberts

      Affiliations

    • MARIAC, University of Liverpool, Liverpool, L69 3GE, UK
    • ,
  • Clare E. Mackay

      Affiliations

    • Department of Psychiatry, Oxford University, Oxford, UK

Received 1 July 2009 ,Revised 22 September 2009 ,Accepted 28 December 2009.

References 

  1. Barrick TR, Mackay CE, Crow TJ, Maes F, Vandermeulen D, Roberts N. Analysis of asymmetry in 2D and 1D projections of left and right cerebral hemisphere grey and white matter. Neuroimage. 2001;13:72
  2. Barrick TR, Mackay CE, Prima S, Vandermeulen D, Crow TJ, Roberts N. Automatic analysis of cerebral asymmetry: an exploratory study of the relationship between brain torque and planum temporale asymmetry. Neuroimage. 2005;24:678–691
  3. Crow TJ. Schizophrenia as failure of hemispheric dominance for language. Trends Neurosci. 1997;20:339–343
  4. Geschwind N, Levitsky W. Human brain: left–right asymmetry in temporal speech region. Science. 1968;161:186–187
  5. Hadjulis M, Pipe R, Frangou S. Normal cerebral volume asymmetries in early onset schizophrenia. Biol. Psychiatry. 2004;55:148–153
  6. Harasty J, Seldon HL, Chan P, Halliday G, Harding A. The left human speech-processing cortex is thinner but longer than the right. Laterality. 2003;8(3):247–260
  7. Jacobsen LK, Giedd JN, Tanrikut C, Brady DR, Donohue BC, Hamburger SD, et al. Three dimensional cortical morphometry of the planum temporale in childhood onset schizophrenia. Am. J. Psychiatry. 1997;154:685–687
  8. Mackay CE, Barrick TR, Roberts N, DeLisi LE, Maes F, Vandermeulen D, et al. Application of a new image analysis technique to study brain asymmetry in schizophrenia. Psychiatry Res. Neuroimaging. 2003;124:25–35
  9. Nasrallah HA. The unintegrated right cerebral hemispheric consciousness as alien intruder: a possible mechanism for Schneiderian delusions in schizophrenia. Compr. Psychiatry. 1985;26:273–282
  10. Shapleske J, Rossell SL, Woodruff PW, David AS. The planum temporale: a systematic, quantitative review of its structural, functional and clinical significance. Brain Res. Rev. 1999;29:26–49
  11. Sommer I, Ramsey N, Kahn S, Aleman A, Bouma A. Handedness, language lateralisation and anatomical asymmetry in schizophrenia: meta-analysis. Br. J. Psychiatry. 2001;178:344–351
  12. Sowell ER, Thompson PM, Rex D, Kornsand D, Tessner KD, Jernigan TL, et al. Mapping sulcal pattern asymmetry and local cortical surface gray matter distribution in vivo: maturation in perisylvian cortices. Cereb. Cortex. 2002;12:17–26

PII: S0920-9964(09)00623-9

doi: 10.1016/j.schres.2009.12.032

Schizophrenia Research
Volume 120, Issue 1 , Pages 84-86 , July 2010

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