Schizophrenia Research
Volume 121, Issue 1 , Pages 101-106 , August 2010

Superior size–weight illusion performance in patients with schizophrenia: Evidence for deficits in forward models

  • Lisa E. Williams

      Affiliations

    • Department of Psychology, University of California San Diego, 9500 Gilman Drive #0109, La Jolla, CA 92093-0109, USA
    • Center for Brain and Cognition, University of California San Diego, 9500 Gilman Drive #0109, La Jolla, CA 92093-0109, USA
    • Corresponding Author InformationCorresponding author. Department of Psychiatry, Vanderbilt University, 1601 23rd Ave S., Suite 3060, USA. Tel.: +1 615 343 8068; fax: +1 615 343 8406.
  • ,
  • Vilayanur S. Ramachandran

      Affiliations

    • Department of Psychology, University of California San Diego, 9500 Gilman Drive #0109, La Jolla, CA 92093-0109, USA
    • Center for Brain and Cognition, University of California San Diego, 9500 Gilman Drive #0109, La Jolla, CA 92093-0109, USA
  • ,
  • Edward M. Hubbard

      Affiliations

    • Department of Psychology and Human Development, Vanderbilt University, Peabody College #552, 230 Appleton Place, Nashville, TN 37203-5721, USA
  • ,
  • David L. Braff

      Affiliations

    • Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0804C, USA
  • ,
  • Gregory A. Light

      Affiliations

    • Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0804C, USA

Received 9 August 2009 ,Revised 13 October 2009 ,Accepted 19 October 2009.

References 

  1. Andreasen NC. Scale for the Assessment of Negative Symptoms (SANS). Iowa City, Iowa: University of Iowa; 1984;
  2. Andreasen NC. Scale for the Assessment of Positive Symptoms (SAPS). Iowa City, Iowa: University of Iowa; 1984;
  3. Andreasen NC, Pierson R. The role of the cerebellum in schizophrenia. Biol. Psychiatry. 2008;64(2):81–88
  4. Blakemore SJ, Smith J, Steel R, Johnstone CE, Frith CD. The perception of self-produced sensory stimuli in patients with auditory hallucinations and passivity experiences: evidence for a breakdown in self-monitoring. Psychol. Med. 2000;30(5):1131–1139
  5. Braff DL. Information processing and attention dysfunctions in schizophrenia. Schizophr. Bull. 1993;19(2):233–259
  6. Charpentier A. Analyse experimentale de quelques elements de la sensation de poids [Experimental analysis of some elements of weight sensations]. Arch. Physiol. Norm. Pathol. 1891;3:122–135
  7. Chouinard PA, Large ME, Chang EC, Goodale MA. Dissociable neural mechanisms for determining the perceived heaviness of objects and the predicted weight of objects during lifting: an fMRI investigation of the size–weight illusion. NeuroImage. 2009;44(1):200–212
  8. Danckert J, Saoud M, Maruff P. Attention, motor control and motor imagery in schizophrenia: implications for the role of the parietal cortex. Schizophr. Res. 2004;70(2–3):241–261
  9. Davison AC, Hinkley D. Bootstrap Methods and their Application. 8th ed.. New York, NY: Cambridge University Press; 2006;
  10. de Gelder B, Vroomen J, Annen L, Masthof E, Hodiamont P. Audio-visual integration in schizophrenia. Schizophr. Res. 2003;59(2–3):211–218
  11. de Gelder B, Vroomen J, de Jong SJ, Masthoff ED, Trompenaars FJ, Hodiamont P. Multisensory integration of emotional faces and voices in schizophrenics. Schizophr. Res. 2005;72(2–3):195–203
  12. de Jong JJ, Hodiamont PP, Van den Stock J, de Gelder B. Audiovisual emotion recognition in schizophrenia: reduced integration of facial and vocal affect. Schizophr. Res. 2009;107(2–3):286–293
  13. Efron B, Tibshirani RJ. An Introduction to the Bootstrap. New York, NY: Chapman & Hall; 1993;
  14. Ellis RR, Lederman SJ. The role of haptic versus visual volume cues in the size–weight illusion. Percept. Psychophys. 1993;53(3):315–324
  15. Ellis RR, Lederman SJ. The golf-ball illusion: evidence for top-down processing in weight perception. Perception. 1998;27(2):193–201
  16. Feinberg I. Efference copy and corollary discharge: implications for thinking and its disorders. Schizophr. Bull. 1978;4(4):636–640
  17. Flanagan JR, Beltzner MA. Independence of perceptual and sensorimotor predictions in the size–weight illusion. Nat. Neurosci. 2000;3(7):737–741
  18. Flanagan JR, Bittner JP, Johansson RS. Experience can change distinct size–weight priors engaged in lifting objects and judging their weights. Curr. Biol. 2008;18(22):1742–1747
  19. Ford JM, Mathalon DH. Corollary discharge dysfunction in schizophrenia: can it explain auditory hallucinations?. Int. J. Psychophysiol. 2005;58(2–3):179–189
  20. Ford JM, Mathalon DH, Heinks T, Kalba S, Faustman WO, Roth WT. Neurophysiological evidence of corollary discharge dysfunction in schizophrenia. Am. J. Psychiatry. 2001;158(12):2069–2071
  21. Ford JM, Mathalon DH, Kalba S, Whitfield S, Faustman WO, Roth WT. Cortical responsiveness during inner speech in schizophrenia: an event-related potential study. Am. J. Psychiatry. 2001;158(11):1914–1916
  22. Ford JM, Roach BJ, Faustman WO, Mathalon DH. Out-of-synch and out-of-sorts: dysfunction of motor-sensory communication in schizophrenia. Biol. Psychiatry. 2007;63(8):736–743
  23. Frith CD. The positive and negative symptoms of schizophrenia reflect impairments in the perception and initiation of action. Psychol. Med. 1987;17(3):631–648
  24. Gescheider GA. Psychophysics: the Fundamentals. Mahwah, NJ: Lawrence Erlbaum Associates; 1997;
  25. Grandy MS, Westwood DA. Opposite perceptual and sensorimotor responses to a size–weight illusion. J. Neurophysiol. 2006;95(6):3887–3892
  26. Holcomb HH, Parwani A, McMahon RP, Medoff DR, Frey K, Lahti AC, et al. Parametric study of accuracy and response time in schizophrenic persons making visual or auditory discriminations. Psychiatry Res. 2004;127(3):207–216
  27. Javitt DC, Liederman E, Cienfuegos A, Shelley AM. Panmodal processing imprecision as a basis for dysfunction of transient memory storage systems in schizophrenia. Schizophr. Bull. 1999;25(4):763–775
  28. Jenmalm P, Schmitz C, Forssberg H, Ehrsson HH. Lighter or heavier than predicted: neural correlates of corrective mechanisms during erroneously programmed lifts. J. Neurosci. 2006;26(35):9015–9021
  29. Jordan MI, Rumelhart DE. Forward models: supervised learning with a distal teacher. Cogn. Sci. 1992;16:307–354
  30. Kawai S, Henigman F, MacKenzie CL, Kuang AB, Faust PH. A reexamination of the size–weight illusion induced by visual size cues. Exp. Brain Res. 2007;179(3):443–456
  31. Leventhal DB, Schuck JR, Clemons JT, Cox M. Proprioception in schizophrenia. J. Nerv. Ment. Dis. 1982;170(1):21–26
  32. Miall RC, Weir DJ, Wolpert DM, Stein JF. Is the Cerebellum a Smith Predictor?. J. Mot. Behav. 1993;25(3):203–216
  33. Nuechterlein KH, Dawson ME. Information processing and attentional functioning in the developmental course of schizophrenic disorders. Schizophr. Bull. 1984;10(2):160–203
  34. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia. 1971;9(1):97–113
  35. Ritzler BA. Proprioception and schizophrenia: a replication study with nonschizophrenic patient controls. J. Abnorm. Psychology. 1977;86(5):501–509
  36. Ross HE. Sensory information necessary for the size–weight illusion. Nature. 1966;212(5062):650
  37. Ross CA, Pearlson GD. Schizophrenia, the heteromodal association neocortex and development: potential for a neurogenetic approach. Trends Neurosci. 1996;19(5):171–176
  38. Ross HE, Gregory RL. Weight illusions and weight discrimination-a revised hypothesis. Q. J. Exp. Psychol. 1970;22(2):318–328
  39. Ross LA, Saint-Amour D, Leavitt VM, Molholm S, Javitt DC, Foxe JJ. Impaired multisensory processing in schizophrenia: deficits in the visual enhancement of speech comprehension under noisy environmental conditions. Schizophr. Res. 2007;97(1–3):173–183
  40. Shergill SS, Samson G, Bays PM, Frith CD, Wolpert DM. Evidence for sensory prediction deficits in schizophrenia. Am. J. Psychiatry. 2005;162(12):2384–2386
  41. Sirigu A, Daprati E, Ciancia S, Giraux P, Nighoghossian N, Posada A, et al. Altered awareness of voluntary action after damage to the parietal cortex. Nat. Neurosci. 2004;7(1):80–84
  42. Torrey EF. Schizophrenia and the inferior parietal lobule. Schizophr. Res. 2007;97(1–3):215–225
  43. Wolpert DM. Computational approaches to motor control. Trends Cogn. Sci. 1997;1:209–216
  44. Wolpert DM, Kawato M. Multiple paired forward and inverse models for motor control. Neural Netw. 1998;11(7–8):1317–1329
  45. Wolpert DM, Miall RC. Forward Models for Physiological Motor Control. Neural Netw. 1996;9(8):1265–1279
  46. Zubin J, Salzinger K, Fleiss JL, Gurland B, Spitzer RL, Endicott J, et al. Biometric approach to psychopathology: abnormal and clinical psychology-statistical, epidemiological, and diagnostic approaches. Annu. Rev. Psychol. 1975;26:621–671

PII: S0920-9964(09)00543-X

doi: 10.1016/j.schres.2009.10.021

Schizophrenia Research
Volume 121, Issue 1 , Pages 101-106 , August 2010