Schizophrenia Research
Volume 116, Issue 1 , Pages 55-60 , January 2010

Maternal schizophrenia and pregnancy outcome: Does the use of antipsychotics make a difference?

  • Herng-Ching Lin

      Affiliations

    • School of Health Care Administration, Taipei Medical University, Taipei, Taiwan
    • Corresponding Author InformationCorresponding author. School of Health Care Administration, Taipei Medical University, 250 Wu-Hsing St., Taipei 110, Taiwan. Tel.: +886 2 2736 1661x3613; fax: +886 2 2378 9788.
    • ,
  • I-Ju Chen

      Affiliations

    • School of Health Care Administration, Taipei Medical University, Taipei, Taiwan
    • Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan
    • ,
  • Yi-Hua Chen

      Affiliations

    • School of Public Health, Taipei Medical University, Taipei, Taiwan
    • ,
  • Hsin-Chien Lee

      Affiliations

    • School of Medicine, Department of Psychiatry, Taipei Medical University, Taipei, Taiwan
    • ,
  • Fang-Jen Wu

      Affiliations

    • College of Pharmacy, Taipei Medical University, Taipei, Taiwan

Received 25 July 2009 ,Revised 13 October 2009 ,Accepted 18 October 2009.

References 

  1. ACOG Practice Bulletin. Clinical management guidelines for obstetrician–gynecologists number 92, April 2008 (replaces practice bulletin number 87, November 2007). Use of psychiatric medications during pregnancy and lactation. Obstet. Gynecol. 2008;111:1001–1020
  2. Falterman CG, Richardson CJ. Small left colon syndrome associated with maternal ingestion of psychotropic drugs. J. Pediatr. 1980;97:308–310
  3. Gentile S. Clinical utilization of atypical antipsychotics in pregnancy and lactation. Ann. Pharmacother. 2004;38:1265–1271
  4. Hauser LA. Pregnancy and psychiatric drugs. Hosp. Community Psychiatr. 1985;36:817–818
  5. Jablensky AV, Morgan V, Zubrick SR, Bower C, Yellachich LA. Pregnancy, delivery, and neonatal complications in a population cohort of women with schizophrenia and major affective disorders. Am. J. Psychiatry. 2005;162:79–91
  6. Jansson L, Handest P, Nielsen J, Sæbye D, Parnas J. Exploring boundaries of schizophrenia: a comparison of ICD-10 with other diagnostic systems in first-admitted patients. World Psychiatry. 2002;1:109–114
  7. Kohen D. Psychotropic medication in pregnancy. Adv. Psychiatr. Treat. 2004;10:59–66
  8. McCormick MC. The contribution of low birth weight to infant mortality and childhood morbidity. N. Engl. J. Med. 1985;312:82–90
  9. McKenna K, Koren G, Tetelbaum M, Wilton L, Shakir S, Diav-Citrin O, et al. Pregnancy outcome of women using atypical antipsychotic drugs: a prospective comparative study. J. Clin. Psychiatry. 2005;66:444–449
  10. Menon SJ. Psychotropic medication during pregnancy and lactation. Arch. Gynecol. Obstet. 2008;277:1–13
  11. Miller LJ. Sexuality, reproduction, and family planning in women with schizophrenia. Schizophr. Bull. 1997;23:623–635
  12. Newham JJ, Thomas SH, MacRitchie K, McElhatton PR, McAllister-Williams RH. Birth weight of infants after maternal exposure to typical and atypical antipsychotics: prospective comparison study. Br. J. Psychiatry. 2008;192:333–337
  13. Newport DJ, Calamaras MR, DeVane CL, Donovan J, Beach AJ, Winn S, et al. Atypical antipsychotic administration during late pregnancy: placental passage and obstetrical outcome. Am. J. Psychiatry. 2007;164:1214–1220
  14. Reis M, Kallen B. Maternal use of antipsychotics in early pregnancy and delivery outcome. J. Clin. Psychopharmacol. 2008;28:279–288
  15. Sacker A, Done DJ, Crow TJ. Obstetric complications in children born to parents with schizophrenia: a meta-analysis of case–control studies. Psychol. Med. 1996;26:279–287
  16. Wisner KL, Sit DK, Moses EL. Antipsychotic treatment during pregnancy: a model for decision making. Adv. Schizophr. Clin. Psychol. 2007;3:48–55

PII: S0920-9964(09)00498-8

doi: 10.1016/j.schres.2009.10.011

Schizophrenia Research
Volume 116, Issue 1 , Pages 55-60 , January 2010

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