Schizophrenia Research
Volume 116, Issue 2 , Pages 289-290 , February 2010

RE: Familial aggregation of clinical and neurocognitive features in sibling pairs with and without schizophrenia

  • Janice A. Husted

      Affiliations

    • Department of Health Studies and Gerontology, University of Waterloo, Waterloo, 200 University Avenue West, Waterloo, Ontario, Canada N2L 3G1
    • Corresponding Author InformationCorresponding author. Tel.: +519 885 1211; fax: +519 746 2510.
    • ,
  • Celia Greenwood

      Affiliations

    • Program in Genetics and Genomic Biology, Hospital for Sick Children, Research Institute, Toronto, Ontario, Canada
    • ,
  • Anne S. Bassett

      Affiliations

    • Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    • Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada

Received 9 June 2009 ,Revised 26 August 2009 ,Accepted 31 August 2009.

References 

  1. Chen LS, Rice TK, Thompson PA, Barch DM, Csernansky JG. Familial aggregation of clinical and neurocognitive features in sibling pairs with and without schizophrenia. Schizophr. Res. 2009;111:159–166
  2. Glahn DC, Almasy L, Blangero J, Burk GM, Estrada J, Peralta JM, et al. Adjudicating neurocognitive endophenotypes for schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2007;144:242–249
  3. Greenwood TA, Braff DL, Light GA, Cadenhead KS, Calkins ME, Dobie DJ, et al. Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia. Arch. Gen. Psychiatry. 2007;64:1242–1250
  4. Gur RE, Calkins ME, Gur RC, Horan WP, Nuechterlein KH, Seidman LJ, et al. The consortium on the genetics of schizophrenia: neurocognitive endophenotypes. Schizophr. Bull. 2007;33:49–68
  5. Gur RE, Nimgaonkar VL, Almasy L, Calkins ME, Ragland JD, Pogue-Geile MF, et al. Neurocognitive endophenotypes in a multiplex multigenerational family study of schizophrenia. Am. J. Psychiatry. 2007;164:813–819
  6. Husted, J., Chow, E.W.C., Bassett, A.S., 2009. Heritability of neurocognitive traits in familial schizophrenia. Am J Med Genet (Neuropsychiatric Genet) 150B, 845–853.
  7. Toulopoulou T, Picchioni M, Rijsdijk F, Hua-Hall M, Ettinger U, Sham P, et al. Substantial genetic overlap between neurocognition and schizophrenia: genetic modeling in twin samples. Arch. Gen. Psychiatry. 2007;64:1348–1355
  8. Tuulio-Henriksson A, Haukka J, Partonen T, Varilo T, Paunio T, Ekelund J, et al. Heritability and number of quantitative trait loci of neurocognitive functions in families with schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2002;114:438–490
  9. Vieland VJ, Hodge SE. The problem of ascertainment for linkage analysis. Am. J. Hum. Genet. 1996;58:1072–1084

PII: S0920-9964(09)00425-3

doi: 10.1016/j.schres.2009.08.019

Schizophrenia Research
Volume 116, Issue 2 , Pages 289-290 , February 2010

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