Schizophrenia Research
Volume 113, Issue 2 , Pages 123-128 , September 2009

Assessing the impact of cannabis use on trends in diagnosed schizophrenia in the United Kingdom from 1996 to 2005

  • Martin Frisher

      Affiliations

    • Department of Medicines Management, Keele University, Staffordshire, ST5 5BG, United Kingdom
    • Corresponding Author InformationCorresponding author. Tel.: +44 1782 733568; fax: +44 1782 713 586.
    • ,
  • Ilana Crome

      Affiliations

    • Academic Psychiatry Unit, Keele University Medical School, Harplands Hospital, Hilton Road, Staffordshire, ST6 4TH, United Kingdom
    • ,
  • Orsolina Martino

      Affiliations

    • Department of Medicines Management, Keele University, Staffordshire, ST5 5BG, United Kingdom
    • ,
  • Peter Croft

      Affiliations

    • Primary Care Sciences Research Centre, Keele University, Staffordshire, ST5 5BG, United Kingdom

Received 17 April 2009 ,Revised 27 May 2009 ,Accepted 30 May 2009.

References 

  1. Ajdacic-Gross V, Lauber C, Warnke I, Haker H, Murray RM, Rössler W. Changing incidence of psychotic disorders among the young in Zurich. Schizophr. Res. 2007;95:9–18
  2. Arsenault L, Cannon M, Witton J, Murray RM. Causal association between cannabis and psychosis: examination of the evidence. Br. J. Psychiatry. 2004;184:110–117
  3. Burns T, Kendrick T, Cohen A. The primary care of patients with schizophrenia. Schizophr. Res. 1998;29:203
  4. Delgrande Jordan M, Kuntsche E, Schmid H, Kuendig H. Trends im Substanzkonsum von Jugendlichen in der Schweiz [Trends in substance use pattern among adolescents in Switzerland]. Paediatrica. 2004;15:34–35
  5. Department of health . developing the quality and outcomes framework: proposals for a new, independent process. 2008;http://www.dh.gov.uk/en/Consultations/Closedconsultations/DH_089778 [accessed March 24, 2009]
  6. Doll R, Peto R. Mortality and relation to smoking: 20 years observation on male British doctors. BMJ. 1976;1:967–971
  7. EMCDDA . In: A Cannabis Reader: Global Issues and Local Experiences. Monograph series 8. vol. 1:Lisbon: European Monitoring Centre for Drugs and Drug Addiction; 2008;
  8. Ferdinand RF, Sondeijker F, van der Ende J, Selten JP, Huizink A, Verhulst FC. Cannabis use predicts future psychotic symptoms, and vice versa. Addiction. 2005;100:612–618
  9. Frisher M, Crome I, Macleod J, Millson D, Croft P. Substance misuse and psychiatric illness: prospective observational study using the general practice research database. J. Epidemiol. Community Health. 2005;59:847–850
  10. Garcia Rodriguez LA, Pérez Gutthann S. Use of the UK general practice research database for pharmacoepidemiology. Br. J. Clin. Pharmacol. 1998;45:419–425
  11. Gregg L, Barrowclough C, Haddock G. Reasons for increased substance use in psychosis. Clin. Psychol. Rev. 2007;27:494–510
  12. Hickman M, Vickerman P, Macleod J, Kirkbride J, Jones PB. Cannabis and schizophrenia: model projections of the impact of the rise in cannabis use on historical and future trends in schizophrenia in England and Wales. Addiction. 2007;102:597–606
  13. Hides L, Dawe S, Kavanagh DJ, Young McD R. A prospective study of psychotic symptom and cannabis relapse in recent onset psychosis. Br. J. Psychiatry. 2006;189:137–143
  14. Hospital episode statistics online. http://www.hesonline.nhs.uk/[accessed September 29, 2008].
  15. Jane-Lopis E, Matytsina I. Mental health and alcohol, drugs and tobacco: a review of the comorbidity between mental disorders and the use of alcohol, tobacco and illicit drugs. Drug Alcohol Rev. 2006;25:513–536
  16. Jick H, Jick SS, Derby LE. Validation of information recorded on general practitioner based computerised data resource in the United Kingdom. BMJ. 1991;302:766–778
  17. Jick H, Terris BZ, Derby LE, Jick SS. Further validation of information recorded on a general practitioner based computerized data resource in the United Kingdom. Pharmacoepidemiol. Drug Safety. 1992;1:347–349
  18. Kuntsche EN. Progression of a general substance use pattern among adolescents in Switzerland? Investigating the relationship between alcohol, tobacco, and cannabis use over a 12-year period. Eur. Addict. Res. 2004;10:118–125
  19. Lauronen E, Miettunen J, Veijola J, Karhu M, Jones PB, Isohanni M. Outcome and its predictors in schizophrenia within the Northern Finland 1966 Birth Cohort. Eur. Psychiatry. 2007;22:129–136
  20. Macleod J, Davey Smith G, Hickman M. Does cannabis cause schizophrenia?. Lancet. 2006;367:1055
  21. Mensinga T, de Vries I, Kruidenier M, Hunault C, van den Hengel-Koot C, Fijen M, et al. Dubbel-blind, geramndomiseerd, placebogecontroleered, 4-weg gekruist onderzoek naar de farmacokinetik en effecten van cannabis [A double-blind, randomized, placebo-controlled, cross-over study on the pharmacokinetics and effects of cannabis]. In: RIVM rapport 267002001/2006, Bilthoven. 2006;
  22. Moore THM, Zammit S, Lingford-Hughes A, Barnes TRE, Jones PB, Burke M, et al. Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet. 2007;370:319–328
  23. Munk-Jorgensen P, Mortensen PB. Social outcome in schizophrenia: a 13-year follow-up. Soc. Psychiatry Psychiatr. Epidemiol. 1992;27:129–134
  24. Nazareth I, King M, Haines A, Rangel L, Myers S. Accuracy of diagnosis of psychosis on general practice computer system. BMJ. 1993;307:32–34
  25. Office of the Deputy Prime Minister . The English Indices of Multiple Deprivation 2004 (revised). London: ODPM, Neighbourhood Renewal Unit. 2004;
  26. Regier DA, Farmer ME, Rae DS, Locke BZ, Keith SJ, Judd LL, et al. Comorbidity of mental disorders with alcohol and other drug abuse: results from the Epidemiologic Catchment Area (ECA) study. JAMA. 1990;264:2511–2518
  27. Rey JM, Tennant CC. Cannabis and mental health. BMJ. 2002;325:1183–1184
  28. Roe S, Man L. Drug misuse declared: findings from the 2005/06 British Crime Survey (England and Wales). Home Office Statistical Bulletin; 2006;Oct 2006: http://www.homeoffice.gov.uk/rds/pdfs06/hosb1506.pdf (accessed 8 May 2007)
  29. Singleton, N., Bumpstead, R., O'Brien, M., Lee, A., Meltzer, H., 2000. Psychiatric morbidity among adults living in private households. London: The Stationery Office, 2001.
  30. Stats Direct, Stats Direct Ltd. http://www.statsdirect.com/ (accessed 5 Mar 2007).
  31. Zammit S, Moore THM, Lingford-Hughes A, Barnes TRE, Jones PB, Burke M, et al. Effects of cannabis use on outcomes of psychotic disorders: Systematic review. Br. J. Psychiatry. 2008;193:357–363

PII: S0920-9964(09)00269-2

doi: 10.1016/j.schres.2009.05.031

Schizophrenia Research
Volume 113, Issue 2 , Pages 123-128 , September 2009

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