Schizophrenia Research
Volume 108, Issue 1 , Pages 170-175 , March 2009

Obsessive compulsive symptoms in the psychosis prodrome: Correlates of clinical and functional outcome

  • Tara A. Niendam

      Affiliations

    • Department of Psychology, University of California, Los Angeles, 1285 Franz Hall, Box 951563, Los Angeles, CA 90095-1563, United States
    • Corresponding Author InformationCorresponding author. UC Davis Imaging Research Center 4701 X Street, Sacramento, CA 95817, United States Tel.: +916 734 4528; fax: +916 734 8750.
  • ,
  • Jodi Berzak

      Affiliations

    • Department of Psychology, University of California, Los Angeles, 1285 Franz Hall, Box 951563, Los Angeles, CA 90095-1563, United States
  • ,
  • Tyrone D. Cannon

      Affiliations

    • Department of Psychology, University of California, Los Angeles, 1285 Franz Hall, Box 951563, Los Angeles, CA 90095-1563, United States
    • Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Box 956968, Suite 2265, 300 Medical Plaza, Los Angeles, CA 90095-6968, United States
  • ,
  • Carrie E. Bearden

      Affiliations

    • Department of Psychology, University of California, Los Angeles, 1285 Franz Hall, Box 951563, Los Angeles, CA 90095-1563, United States
    • Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Box 956968, Suite 2265, 300 Medical Plaza, Los Angeles, CA 90095-6968, United States

Received 1 August 2008 ,Revised 17 November 2008 ,Accepted 19 November 2008.

References 

  1. Auther AM, Smith CW, Cornblatt BA. Global Functioning: Social scale (GFS). Glen Oaks, NY: Zucker Hillside Hospital; 2006;
  2. Beck AT, Epstein N, Brown G, Steer RA. An inventory for measuring clinical anxiety: psychometric properties. J. Consult. Clin. Psychol. 1988;56:893–897
  3. Berman I, Merson A, Viegner B, Losonczy MF, Pappas D, Green AI. Obsessions and compulsions as a distinct cluster of symptoms in schizophrenia: a neuropsychological study. J. Nerv. Ment. Dis. 1998;186:150–156
  4. Bermanzohn PC. Prevalence and Prognosis of Obsessive–Compulsive Phenomena in Schizophrenia: A Critical View. Psychiatr. Ann. 1999;29:508–512
  5. Bottas A, Cooke RG, Richter MA. Comorbidity and pathophysiology of obsessive–compulsive disorder in schizophrenia: is there evidence for a schizo-obsessive subtype of schizophrenia?. J. Psychiatry Neurosci. 2005;30:187–193
  6. Byerly M, Goodman W, Acholonu W, Bugno R, Rush AJ. Obsessive compulsive symptoms in schizophrenia: frequency and clinical features. Schizophr. Res. 2005;76:309–316
  7. Cannon TD, Cadenhead K, Cornblatt B, Woods SW, Addington J, Walker E, et al. Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. Arch. Gen. Psychiatry. 2008;65:28–37
  8. Cornblatt BA, Auther AM, Niendam T, Smith CW, Zinberg J, Bearden CE, et al. Preliminary findings for two new measures of social and role functioning in the prodromal phase of schizophrenia. Schizophr. Bull. 2007;33:688–702
  9. Eisen JL, Beer DA, Pato MT, Venditto TA, Rasmussen SA. Obsessive–compulsive disorder in patients with schizophrenia or schizoaffective disorder. Am. J. Psychiatry. 1997;154:271–273
  10. Fenton WS, McGlashan TH. The prognostic significance of obsessive–compulsive symptoms in schizophrenia. Am. J. Psychiatry. 1986;143:437–441
  11. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition. (SCID-I/P), Biometrics Research. New York: New York State Psychiatric Institute; 2002;
  12. Foa EB, Kozak MJ, Goodman WK, Hollander E, Jenike MA, Rasmussen SA. DSM-IV field trial: obsessive–compulsive disorder. Am. J. Psychiatry. 1995;152:90–96
  13. Goodman WK, Price LH, Rasmussen SA, Mazure C, Delgado P, Heninger GR, et al. The Yale–Brown Obsessive Compulsive Scale. II. Validity. Arch. Gen. Psychiatry. 1989;46:1012–1016
  14. Gordon A. Obsessions in their relation to psychoses. Am. J. Psychiatry. 1926;82:647–659
  15. Lukoff D, Nuechterlein KH, Ventura J. Manual for the Expanded Brief Psychiatric Rating Scale (BPRS). Schizophr. Bull. 1986;12:594–602
  16. McGlashan TH. Structured Interview for Prodromal Syndromes (SIPS). New Haven: Yale University; 2001;
  17. Meyer SE, Bearden CE, Lux SR, Gordon JL, Johnson JK, O'Brien MP, et al. The psychosis prodrome in adolescent patients viewed through the lens of DSM-IV. J. Child Adolesc. Psychopharmacol. 2005;15:434–451
  18. Miller TJ, McGlashan TH, Rosen JL, Cadenhead K, Cannon T, Ventura J, et al. Prodromal assessment with the structured interview for prodromal syndromes and the scale of prodromal symptoms: predictive validity, interrater reliability, and training to reliability. Schizophr. Bull. 2003;29:703–715
  19. Nechmad A, Ratzoni G, Poyurovsky M, Meged S, Avidan G, Fuchs C, et al. Obsessive–compulsive disorder in adolescent schizophrenia patients. Am. J. Psychiatry. 2003;160:1002–1004
  20. Niendam TA, Bearden CE, Johnson JK, Cannon TD. Global Functioning: Role scale (GFR). Los Angeles: University of California, Los Angeles; 2006;
  21. Poyurovsky M, Hramenkov S, Isakov V, Rauchverger B, Modai I, Schneidman M, et al. Obsessive–compulsive disorder in hospitalized patients with chronic schizophrenia. Psychiatry Res. 2001;102:49–57
  22. Samuel J, Nesdadt G, Wolyniec P, Adler L, Liang K, Pulver A. Obsessive–compulsive symptoms in schizophrenia. Schizophr. Res. 1993;9:139
  23. Sanavio E. Obsessions and compulsions: the Padua Inventory. Behav. Res. Ther. 1988;26:169–177
  24. Stengel E. A study on some clinical aspects of the relationship between obsessional neurosis and psychotic reaction types. J. Ment. Sci. 1945;91:166–187
  25. Sternberger LG, Burns GL. Obsessions and compulsions: psychometric properties of the Padua Inventory with an American college population. Behav. Res. Ther. 1990;28:341–345
  26. Tibbo P, Warneke L. Obsessive–compulsive disorder in schizophrenia: epidemiologic and biologic overlap. J. Psychiatry Neurosci. 1999;24:15–24
  27. Tibbo P, Kroetsch M, Chue P, Warneke L. Obsessive–compulsive disorder in schizophrenia. J. Psychiatr. Res. 2000;34:139–146
  28. Ventura J, Liberman RP, Green MF, Shaner A, Mintz J. Training and quality assurance with the Structured Clinical Interview for DSM-IV (SCID-I/P). Psychiatry Res. 1998;79:163–173
  29. Yung AR, Phillips LJ, Yuen HP, McGorry PD. Risk factors for psychosis in an ultra high-risk group: psychopathology and clinical features. Schizophr. Res. 2004;67:131–142

PII: S0920-9964(08)00526-4

doi: 10.1016/j.schres.2008.11.023

Schizophrenia Research
Volume 108, Issue 1 , Pages 170-175 , March 2009