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Schizophrenia Research
Volume 100, Issue 1
, Pages 86-96
, March 2008
An initial animal proof-of-concept study for central administration of clozapine to schizophrenia patients
References
- . Schizophrenia, sensory gating, and nicotinic receptors. Schizophr. Bull. 1998;24(2):189–202
- . Clozapine-induced agranulocytosis. Incidence and risk factors in the United States. N. Engl. J. Med. 1993;329(3):162–167
- . Neutropenia and agranulocytosis in patients receiving clozapine in the UK and Ireland. Br. J. Psychiatry. 1996;169(4):483–488
- . A double-blind comparative study of clozapine and risperidone in the management of severe chronic schizophrenia. Am. J. Psychiatry. 2001;158(8):1305–1313
- . Comparative efficacy of epidural, subarachnoid, and intracerebroventricular opioids in patients with pain due to cancer. Cochrane Database Syst. Rev. 2005;25(1):CD005178
- . Clozapine-treated subjects with treatment-resistant schizophrenia: a systemic review of experimental and observational studies. Int. Clin. Psychopharmacol. 2002;17(4):189–195
- . Effects of clozapine in schizophrenic outpatients: effects on positive and negative symptoms. Arch. Gen. Psychiatry. 1994;151(1):20–26
- . Positive and negative symptom response to clozapine in schizophrenic patients with and without the deficit syndrome. Am. J. Psychiatry. 1998;155(6):751–760
- . The risks and benefits of clozapine versus chlorpromazine. J. Clin. Psychopharmacol. 1987;7(6):377–384
- . Associations of P50 suppression and desensitization with perceptual and cognitive features of “unreality” in schizotypy. Biol. Psychiatry. 2001;50(6):441–446
- . Neurophysiological and neuropsychological evidence for attentional dysfunction in schizophrenia. Schizophr. Res. 1993;10(2):131–141
- . Intrathecal baclofen for the treatment of spasticity. Acta Neurochir. Suppl. 2007;97(Pt 1):185–188
- . Characterization of nigerlysin, hemolysin produced by Apergillus niger, and effect on mouse neuronal cells in vitro. Toxicol. 2006;219(1-3):150–155
- . P50 abnormalities in schizophrenia: relationship to clinical and neuropsychological indices of attention. Schizophr. Res. 1998;33(3):157–167
- . Clozapine's effectiveness for patients in state hospitals: results from a randomized trial. Psychopharmacol. Bull. 1996;32(4):683–697
- . Long-term course of adolescent schizophrenia. Schizophr. Bull. 2005;31(3):769–780
- . A comparison of the covalent binding of clozapine and olanzapine to human neutrophils in vitro and in vivo. Mol. Pharmacol. 1998;53(6):999–1008
- . Stability indicating methods for the determination of clozapine. J. Pharm. Biomed. Anal. 2002;30(1):35–47
- . Tropisetron improves deficient inhibitory auditory processing in DBA/2 mice: role of α7 nicotinic acetylcholine receptors. Psychopharmacol. 2005;183(1):13–19
- . Clozapine: a clinical review of adverse effects and management. Ann. Clin. Psychiatry. 2003;15(1):33–48
- . Use of 2-hydroxypropyl-beta-cyclodextrin as an intrathecal drug vehicle with opioids. J. Pharmacol. Exp. Ther. 1992;261(2):592–600
- . Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: a suggested solution based on in vivo occupancy. J. Pharmacol. Exp. Ther. 2003;305(2):625–631
- . Intrathecal opioids for intractable pain syndromes. Acta Neurochir. Suppl. 2007;97(pt 1):43–48
- . Implanted drug delivery systems for control of chronic pain. Chapter 19 of Neurosurgical Management of Pain. New York, NY: Springer-Verlag; 1997;
- . Normal P50 suppression in schizophrenia patients treated with atypical antipsychotic medications. Am. J. Psychiatry. 1993;157(5):767–771
- . Current therapy issues and unmet clinical needs in the treatment of schizophrenia: a review of the new generation antipsychotics. Int. Clin. Psychopharmacol. 2005;20(4):183–198
- . CATIE Investigators. Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment. Am. J. Psychiatry. 2006;163(4):600–610
- . Review and management of clozapine side effects. J. Clin. Psychiatry. 2000;61(Suppl 8):14–17
- . The activity of hippocampal interneurons and pyramidal cells during the response of the hippocampus to repeated auditory stimuli. Neurosci. 1995;69:371–381
- . Gating of auditory P50 in schizophrenics: unique effects of clozapine. Biol. Psychiatry. 1996;40(3):181–188
- . Auditory P50 in schizophrenics on clozapine: improved gating parallels clinical improvement and changes in plasma 3-methoxy-hydroxyphenylglycol. Neuropsychobiology. 1999;39(1):10–17
- . Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia. Arch. Gen. Psychiatry. 2006;63(6):630–638
- . Involvement of 5-HT1A receptors in animal tests of anxiety and depression: evidence from genetic models. Stress. 2003;6(2):101–110
- . Schizophrenia-relevant behavioral testing in rodent models: a uniquely human disorder?. Biol. Psychiatry. 2006;59(12):1198–1207
- . Alpha4beta2 nicotinic receptor stimulation contributes to the effects of nicotine in the DBA/2 mouse model of sensory gating. Psychopharmacol. (Berl). 2006;187(1):47–55
- . Suicide prevention effects associated with clozapine therapy in schizophrenia and schizoaffective disorder. Psychiatr. Serv. 1998;49(8):1029–1033
- . Intrathecal baclofen in the treatment of spasticity, dystonia and vegetative disorders. Acta Neurochir. Suppl. 2007;97(Pt 1):213–218
- . Effect of intracerebroventricular continuous infusion of valproic acid versus single i.p. and i.c.v. injections in the amygdala kindling epilepsy model. Epilepsy Res. 2006;70(1):15–26
- . Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat. Neuropsychopharmacol. 2002;26(5):583–594
- . Clozapine improves deficient inhibitory auditory processing in DBA/2 mice, via a nicotinic cholinergic mechanism. Psychopharmacol. 2003;165(4):386–396
- . Genetic correlation of inhibitory gating of hippocampal auditory evoked response and alpha-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains. Neurospychopharmacol. 1996;15(2):152–162
- . Selective alpha-7 nicotinic agonists normalize inhibition of auditory response in DBA/2 mice. Psychopharmacol. 1998;136(4):320–327
- . Equivalent occupancy of dopamine D1 and D2 receptors with clozapine: differentiation from other atypical antipsychotics. Am. J. Psychiatry. 2004;161(9):1620–1625
- . Clozapine, olanzapine, risperidone, and haloperidol in the treatment of patients with chronic schizophrenia and schizoaffective disorder. Am. J. Psychiatry. 2002;159(2):255–262
- . Spinal systems and pain processing: development of novel analgesic drugs with mechanistically defined models. Trends Pharmacol. Sci. 1999;20(8):329–337
- . The utility of 2-hydroxypropyl-beta-cyclodextrin as a vehicle for the intracerebral and intrathecal administration of drugs. Life Sci. 1991;48(7):623–633
PII: S0920-9964(07)00470-7
doi: 10.1016/j.schres.2007.10.012
© 2007 Elsevier B.V. All rights reserved.
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Schizophrenia Research
Volume 100, Issue 1
, Pages 86-96
, March 2008
