Schizophrenia Research
Volume 93, Issue 1 , Pages 42-50 , July 2007

A single 20 mg dose of dihydrexidine (DAR-0100), a full dopamine D1 agonist, is safe and tolerated in patients with schizophrenia

  • Mark S. George

      Affiliations

    • Brain Stimulation Laboratory (BSL), Psychiatry Department, Medical University of South Carolina (MUSC) 29425, United States
    • Corresponding Author InformationCorresponding author. 67 President Street, Room 502 N IOP Charleston, SC, 29425, United States. Tel.: +1 843 876 5142; fax: +1 843 792 5702.
  • ,
  • Christine E. Molnar

      Affiliations

    • Brain Stimulation Laboratory (BSL), Psychiatry Department, Medical University of South Carolina (MUSC) 29425, United States
  • ,
  • Emily L. Grenesko

      Affiliations

    • Brain Stimulation Laboratory (BSL), Psychiatry Department, Medical University of South Carolina (MUSC) 29425, United States
  • ,
  • Berry Anderson

      Affiliations

    • Brain Stimulation Laboratory (BSL), Psychiatry Department, Medical University of South Carolina (MUSC) 29425, United States
  • ,
  • Qiwen Mu

      Affiliations

    • Brain Stimulation Laboratory (BSL), Psychiatry Department, Medical University of South Carolina (MUSC) 29425, United States
  • ,
  • Kevin Johnson

      Affiliations

    • Brain Stimulation Laboratory (BSL), Psychiatry Department, Medical University of South Carolina (MUSC) 29425, United States
  • ,
  • Ziad Nahas

      Affiliations

    • Brain Stimulation Laboratory (BSL), Psychiatry Department, Medical University of South Carolina (MUSC) 29425, United States
  • ,
  • Michael Knable

      Affiliations

    • Stanley Medical Research Institute, Bethesda MD 20814, United States
  • ,
  • Prabhavathi Fernandes

      Affiliations

    • Formerly of DarPharma Inc, Raleigh, NC, United States
  • ,
  • Jorge Juncos

      Affiliations

    • Department of Neurology, Emory University School of Medicine, Atlanta GA 30329, United States
  • ,
  • Xuemei Huang

      Affiliations

    • Departments of Neurology (XH, RBM), and Psychiatry, Pharmacology and Medicinal Chemistry (RBM), University of North Carolina School of Medicine, Chapel Hill, NC 27599, United States
  • ,
  • David E. Nichols

      Affiliations

    • Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, W. Lafayette IN 47907, United States
  • ,
  • Richard B. Mailman

      Affiliations

    • Departments of Neurology (XH, RBM), and Psychiatry, Pharmacology and Medicinal Chemistry (RBM), University of North Carolina School of Medicine, Chapel Hill, NC 27599, United States

Received 2 October 2006 ,Revised 28 February 2007 ,Accepted 5 March 2007.

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PII: S0920-9964(07)00119-3

doi: 10.1016/j.schres.2007.03.011

Schizophrenia Research
Volume 93, Issue 1 , Pages 42-50 , July 2007