Schizophrenia Research
Volume 92, Issue 1 , Pages 15-23 , May 2007

Mixed-handedness is associated with the reporting of psychotic-like beliefs in a non-clinical Italian sample

  • Antonio Preti

      Affiliations

    • Department of Psychology, University of Cagliari, via Is Mirrionis 1, 09123 Cagliari, Italy
    • Genneruxi Medical Center, via Costantinopoli 42, 09129 Cagliari, Italy
    • Corresponding Author InformationCorresponding author. Genneruxi Medical Center, via Costantinopoli 42, 09129 Cagliari, Italy.
    • ,
  • Cinzia Sardu

      Affiliations

    • Department of Psychology, University of Cagliari, via Is Mirrionis 1, 09123 Cagliari, Italy
    • ,
  • Annalisa Piga

      Affiliations

    • Department of Psychology, University of Cagliari, via Is Mirrionis 1, 09123 Cagliari, Italy

Received 13 December 2006 ,Revised 30 January 2007 ,Accepted 31 January 2007.

References 

  1. Annett M. A classification of hand preference by association analysis. Br. J. Psychol. 1970;61:303–321
  2. Annett M. The right shift theory of a genetic balanced polymorphism for cerebral dominance and cognitive processing. Curr. Psychol. Cogn. 1995;14:1–54
  3. Annett M. Handedness and cerebral dominance: the right shift theory. J. Neuropsychiatry. 1998;10:459–469
  4. Annett M, Moran P. Schizotypy is increased in mixed-handers, especially right-handed writers who use the left hand for primary actions. Schizophr. Res. 2006;81:239–246
  5. Arseneault L, Cannon M, Poulton R, Murray R, Caspi A, Moffitt TE. Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study. BMJ. 2002;325:1212–1213
  6. Barnett KJ, Corballis MC. Ambidexterity and magical ideation. Laterality. 2002;7:75–84
  7. Bell V, Halligan PW, Ellis HD. Explaining delusions: a cognitive perspective. Trends Cogn. Sci. 2006;10:219–226
  8. Bishop DVM. Handedness and Developmental Disorder. Hove: Lawrence Erlbaum; 1990;
  9. Braff DL, Geyer MA. Sensorimotor gating and schizophrenia. Arch. Gen. Psychiatry. 1990;47:181–188
  10. Cannon M, Byrne M, Cassidy B, Larkin C, Horgan R, Sheppard NP, et al. Prevalence and correlates of mixed-handedness in schizophrenia. Psychiatry Res. 1995;59:119–125
  11. Cannon M, Jones PB, Murray RM. Obstetric complications and schizophrenia: historical and meta-analytic review. Am. J. Psychiatry. 2002;159:1080–1092
  12. Chapman JP, Chapman LJ. Handedness and hypothetically psychosis-prone subjects. J. Abnorm. Psychology. 1987;96:89–93
  13. Chen WJ, Su CH. Handedness and schizotypy in non-clinical populations: influence of handedness measures and age on the relationship. Laterality. 2006;11:331–349
  14. Claridge G, Clark K, Davis C, Mason O. Schizophrenia risk and handedness: a mixed picture. Laterality. 1998;3:209–220
  15. Coude FX, Mignot C, Lyonnet S, Munnich A. Discontinuity in the fall of left-handedness in a French population: a May '68 effect?. Laterality. 2006;11:33–35
  16. Crow TJ. Temporal lobe asymmetries as the key to the aetiology of schizophrenia. Schizophr. Bull. 1990;16:433–443
  17. Crow TJ. Cerebral asymmetry and the lateralization of language: core deficits in schizophrenia as pointers to the gene. Curr. Opin. Psychiatry. 2004;17:97–106
  18. Crow TJ, Done DJ, Sacker A. Cerebral lateralization is delayed in children who later develop schizophrenia. Schizophr. Res. 1996;22:181–185
  19. DeLisi LE, Svetina C, Razi K, Shields G, Wellman N, Crow TJ. Hand preference and hand skill in families with schizophrenia. Laterality. 2002;7:321–332
  20. Dellatolas G, Tubert P, Castresana A, Mesbah M, Giallonardo T, Lazaratou H, et al. Age and cohort effects in adult handedness. Neuropsychologia. 1991;29:255–261
  21. Dragovic M. Categorization and validation of handedness using latent class analysis. Acta Neuropsychiatr. 2004;16:212–218
  22. Dragovic M, Hammond G. Handedness in schizophrenia: a quantitative review of evidence. Acta Psychiatr. Scand. 2005;111:410–419
  23. Dragovic M, Hammond G, Badcock JC, Jablensly A. Laterality phenotypes in patients with schizophrenia, their siblings and controls: associations with clinical and cognitive variables. Br. J. Psychiatry. 2005;187:221–228
  24. Ellett L, Lopes B, Chadwick P. Paranoia in a non-clinical population of college students. J. Nerv. Ment. Dis. 2003;191:425–430
  25. Erlenmeyer-Kimling L, Hans S, Ingraham L, Marcus J, Wynne L, Rehman A, et al. Handedness in children of schizophrenic parents: data from three high-risk studies. Behav. Genet. 2005;35:351–358
  26. Faustman WO, Moses JA, Ringo DL, Newcomer JW. Left-handedness in male schizophrenic patients is associated with increased impairment on the Luria–Nebraska Neuropsychological Battery. Biol. Psychiatry. 1991;30:326–334
  27. Freeman D, Garety PA, Bebbington PE, Smith B, Rollinson R, Fowler D, et al. Psychological investigation of the structure of paranoia in a non-clinical population. Br. J. Psychiatry. 2005;186:427–435
  28. Freeman D, Dunn G, Garety PA, Bebbington P, Slater M, Kuipers E, et al. The psychology of persecutory ideation I. A questionnaire survey. J. Nerv. Ment. Dis. 2005;193:302–308
  29. Freeman D, Garety PA, Bebbington P, Slater M, Kuipers E, Fowler D, et al. The psychology of persecutory ideation II. A virtual reality experimental study. J. Nerv. Ment. Dis. 2005;193:309–315
  30. Galobardes B, Bernstein MS, Morabia A. The association between switching hand preference and the declining prevalence of left-handedness with age. Am. J. Public Health. 1999;89:1873–1875
  31. Goldberg DP. The Detection of Psychiatric Illness by Questionnaire. London: Oxford University Press; 1972;
  32. Gregory AM, Claridge G, Clark K, Taylor PD. Handedness and schizotypy in a Japanese sample: an association masked by cultural effects on hand usage. Schizophr. Res. 2003;65:139–145
  33. Gur RE. Motoric laterality imbalance in schizophrenia. A possible concomitant of left hemisphere dysfunction. Arch. Gen. Psychiatry. 1977;34:33–37
  34. Hollister JM, Laing P, Mednick SA. Rhesus incompatibility as a risk factor for schizophrenia in male adults. Arch. Gen. Psychiatry. 1996;53:19–24
  35. Jablensky AV, Morgan V, Zubrick SR, Bower C, Yellachich LA. Pregnancy, delivery, and neonatal complications in a population cohort of women with schizophrenia and major affective disorders. Am. J. Psychiatry. 2005;162:79–91
  36. Johns LC, Cannon M, Singleton N, Murray RM, Farrell M, Brugha T, et al. Prevalence and correlates of self-reported psychotic symptoms in the British population. Br. J. Psychiatry. 2004;185:298–305
  37. Kendell RE, McInneny K, Juszczak E, Bain M. Obstetric complications and schizophrenia. Two case-control studies based on structured obstetric records. Br. J. Psychiatry. 2000;176:516–522
  38. Kim D, Raine A, Triphon N, Green MF. Mixed handedness and features of schizotypal personality in a nonclinical sample. J. Nerv. Ment. Dis. 1992;180:133–135
  39. Klimkeit EI, Bradshaw JL. Anomalous lateralisation in neurodevelopmental disorders. Cortex. 2006;42:113–116
  40. Lopez-Ilundain JM, Perez-Nievas E, Otero M, Mata I. Peter's delusions inventory in Spanish general population: internal reliability, factor structure and association with demographic variables (dimensionality of delusional ideation). Actas Esp. Psiquiatr. 2006;34:94–104
  41. Lundberg P, Cantor-Graae E, Kabakyenga J, Rukundo G, Ostergren PO. Prevalence of delusional ideation in a district in southwestern Uganda. Schizophr. Res. 2004;71:27–34
  42. Maher BA. Delusional thinking and perceptual disorder. J. Individ. Psychol. 1974;30:98–113
  43. Maher BA, Ross JC. Delusions. In:  Adams HE,  Sutker P editor. Comprehensive Handbook of Psychopathology. New York: Plenum; 1984;p. 383–411
  44. McKeever WF, Suter J, Rich DA. Maternal age and parity correlates of handedness: gender, but no parental handedness modulation of effects. Cortex. 1995;31:543–553
  45. Morrison AP, Haddock G. Cognitive factors in source monitoring and auditory hallucinations. Psychol. Med. 1997;27:669–679
  46. Nicholls ME, Orr CA, Lindell AK. Magical ideation and its relation to lateral preference. Laterality. 2005;10:503–515
  47. Nunn JA, Rizza F, Peters ER. The incidence of schizotypy among cannabis and alcohol users. J. Nerv. Ment. Dis. 2001;189:741–748
  48. Palmer CG, Hsieh HJ, Reed EF, Lonnqvist J, Peltonen L, Woodward JA, et al. HLA-B maternal–fetal genotype matching increases risk of schizophrenia. Am. J. Hum. Genet. 2006;79:710–715
  49. Peters ER, Joseph SA, Garety PA. The measurement of delusional ideation in the normal population: introducing the PDI (Peters et al., Delusions Inventory). Schizophr. Bull. 1999;25:553–576
  50. Peters E, Joseph S, Day S, Garety P. Measuring delusional ideation: the 21-item Peters et al., Delusions Inventory (PDI). Schizophr. Bull. 2004;30:1005–1022
  51. Peters M, Reimers S, Manning JT. Hand preference for writing and associations with selected demographic and behavioral variables in 255,100 subjects: the BBC internet study. Brain Cogn. 2006;62:177–189
  52. Politi PL, Piccinelli M, Wilkinson G. Reliability, validity and factor structure of the 12-item General Health Questionnaire among young males in Italy. Acta Psychiatr. Scand. 1994;90:432–437
  53. Poreh AM, Levin J, Teves H, States J. Mixed handedness and schizotypal personality in a non-clinical sample—the role of task demand. Pers. Individ. Differ. 1997;23:501–507
  54. Preti A, Miotto P. Genetics, perinatal insult, and schizophrenia: the mechanism underlying an increased prevalence of perinatal complications among individuals with a diagnosis of schizophrenia?. Curr. Psychiatry Rev. 2005;1:139–150
  55. Preti A, Marongiu S, Petretto DR, Miotto P, Masala C. Esperienze psichiche inusuali. Studio di validazione della versione italiana del Peters et al., Delusions Inventory (Italian). Riv. Sper. Freniatr. 2002;126:81–100
  56. Preti A, Rocchi MBL, Sisti D, Mura T, Manca S, Siddi S, et al. The psychometric discriminative properties of the Peters et al. Delusions Inventory: a receiver operating characteristic curve analysis. Compr. Psychiatry. 2007;48:62–69
  57. Richardson AJ. Dyslexia, handedness and syndromes of psychosis-proneness. Int. J. Psychophysiol. 1994;18:251–263
  58. Sacker A, Done DJ, Crow TJ, Golding J. Antecedents of schizophrenia and affective illness. Obstetric complications. Br. J. Psychiatry. 1995;166:734–741
  59. Satz P, Green MF. Atypical handedness in schizophrenia: some methodological and theoretical issues. Schizophr. Res. 1999;25:63–78
  60. Schiffman J, Pestle S, Mednick S, Ekstrom M, Sorensen H, Mednick S. Childhood laterality and adult schizophrenia spectrum disorders: a prospective investigation. Schizophr. Res. 2005;72:151–160
  61. Shaw J, Claridge G, Clark K. Schizotypy and shift from dextrality: a study of handedness in a large non-clinical sample. Schizophr. Res. 2001;50:181–189
  62. Sommer I, Aleman A, Ramsey N, Bouma A, Kahn R. Handedness, language lateralisation and anatomical asymmetry in schizophrenia. Br. J. Psychiatry. 2001;178:344–351
  63. Sperling W, Martus P, Barocka A. Non-right-handedness and obstetrical complications in paranoid hallucinatory schizophrenics. Psychopathology. 1999;32:267–276
  64. Stefanis NC, Delespaul P, Henquet C, Bakoula C, Stefanis CN, van Os J. Early adolescent cannabis exposure and positive and negative dimensions of psychosis. Addiction. 2004;99:1333–1341
  65. Stefanis NC, Vitoratou S, Smyrnis N, Constantinidis T, Evdokimidis I, Hatzimanolis I, et al. Mixed handedness is associated with the disorganization dimension of schizotypy in a young male population. Schizophr. Res. 2006;87:289–296
  66. Tyler M, Diamond J, Lewis S. Correlates of left-handedness in a large sample of schizophrenic patients. Schizophr. Res. 1995;18:37–41
  67. van Os J, Bak M, Hanssen M, Bijl RV, de Graaf R, Verdoux H. Cannabis use and psychosis: a longitudinal population-based study. Am. J. Epidemiol. 2002;156:319–327
  68. van Strien JW, Bouma A, Bakker DJ. Birth stress, autoimmune diseases, and handedness. J. Clin. Exp. Neuropsychol. 1987;9:775–780
  69. Verdoux H. Perinatal risk factors for schizophrenia: how specific are they?. Curr. Psychiatry Rep. 2004;6:162–167
  70. Verdoux H, van Os J, Maurice-Tison S, Gay B, Salamon R, Bourgeois M. Is early adulthood a critical developmental stage for psychosis proneness? A survey of delusional ideation in normal subjects. Schizophr. Res. 1998;29:247–254
  71. Verdoux H, van Os J, Maurice-Tison S, Gay B, Salamon R, Bourgeois ML. Increased occurrence of depression in psychosis-prone subjects: a follow-up study in primary care settings. Compr. Psychiatry. 1999;40:462–468
  72. Verdoux H, Sorbara F, Gindre C, Swedsen JD, van Os J. Cannabis use and dimensions of psychosis in a nonclinical population of female subjects. Schizophr. Res. 2002;59:77–84
  73. Whitty P, Clarke M, McTigue O, Browne S, Gervin M, Kamali M, et al. Diagnostic specificity and predictors of neurological soft signs in schizophrenia, bipolar disorder and other psychoses over the first 4 years of illness. Schizophr. Res. 2006;86:110–117
  74. Wing J, Cooperm J, Sartorius N. Measurement and Classification of Psychiatric Symptoms. Cambridge: Cambridge University Press; 1974;

PII: S0920-9964(07)00078-3

doi: 10.1016/j.schres.2007.01.028

Schizophrenia Research
Volume 92, Issue 1 , Pages 15-23 , May 2007

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