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Schizophrenia Research
Volume 91, Issue 1
, Pages 51-61
, March 2007
Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder
References
- . Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2005;134(1):60–66
- . Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics. Arch. Gen. Psychiatry. 1995;52(4):258–266
- . Strange feelings: do amygdala abnormalities dysregulate the emotional brain in schizophrenia?. Prog. Neurobiol. 2005;77(5):283–298
- . Diagnostic and Statistical Manual of Mental Disorders. Fourth edition. Washington, DC: American Psychiatric Association; 1994;
- . Projections from the amygdala to basoventral and mediodorsal prefrontal regions in the rhesus monkey. J. Comp. Neurol. 1990;300(4):549–571
- . Modulation of synaptic plasticity and memory by reelin involves differential splicing of the lipoprotein receptor Apoer2. Neuron. 2005;47(4):567–579
- . GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology. 2001;25(1):1–27
- . Increased GABAA receptor binding in superficial layers of cingulate cortex in schizophrenics. J. Neurosci. 1992;12(3):924–929
- . The expression of proapoptosis genes is increased in bipolar disorder, but not in schizophrenia. Mol. Psychiatry. 2006;11(3):241–251
- . DNA methyltransferase inhibitors: old and new drugs for an epigenetic cancer therapy. Trends Pharmacol. Sci. 2004;25(11):551–554
- . Enhanced dizocilpine efficacy in heterozygous reeler mice relates to GABA turnover downregulation. Neuropharmacology. 2004;46(8):1070–1081
- . On the epigenetic regulation of the human reelin promoter. Nucleic Acids Res. 2002;30(13):2930–2939
- . Dendritic spine hypoplasticity and downregulation of reelin and GABAergic tone in schizophrenia vulnerability. Neurobiol. Dis. 2001;8(5):723–742
- . Reelin and schizophrenia: a disease at the interface of the genome and the epigenome. Mol. Interv. 2002;2(1):47–57
- . Epigenetic downregulation of GABAergic function in schizophrenia: potential for pharmacological intervention?. Mol. Interv. 2003;3(4):220–229
- . GABAergic cortical neuron chromatin as a putative target to treat schizophrenia vulnerability. Crit. Rev. Neurobiol. 2003;15(2):121–142
- . Valproate induces replication-independent active DNA demethylation. J. Biol. Chem. 2003;278(30):27586–27592
- . A reelin-integrin interaction regulates Arc mRNA translation in synaptoneurosomes. Proc. Natl. Acad. Sci. U. S. A. 2003;100(9):5479–5484
- . Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia. Proc. Natl. Acad. Sci. U. S. A. 2005;102(35):12578–12583
- . Interstitial white matter neurons express less reelin and are abnormally distributed in schizophrenia: towards an integration of molecular and morphologic aspects of the neurodevelopmental hypothesis. Mol. Psychiatry. 2003;8(9):821–831
- . Reduction in reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression. Mol. Psychiatry. 2000;5(6):654–663
- . Diagnostic criteria for use in psychiatric research. Arch. Gen. Psychiatry. 1972;26(1):57–63
- . Quantitative distribution of GABA-immunoreactive neurons in the visual cortex (area 17) of the cat. Exp. Brain Res. 1986;61(2):323–331
- . Reelin promoter hypermethylation in schizophrenia. Proc. Natl. Acad. Sci. U. S. A. 2005;102(26):9341–9346
- . The human reelin gene: transcription factors (+), repressors (−) and the methylation switch (+/−) in schizophrenia. Pharmacol. Ther. 2006;111(1):272–286
- . Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study. Arch. Gen. Psychiatry. 2000;57(11):1061–1069
- . GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon. Psychopharmacology (Berl). 2005;180(2):191–205
- . [3H]muscimol binding sites increased in autopsied brains of chronic schizophrenics. Life Sci. 1987;40(3):259–266
- . Transcriptional control of cognitive development. Curr. Opin. Neurobiol. 2005;15(1):21–28
- . A decrease of reelin expression as a putative vulnerability factor in schizophrenia. Proc. Natl. Acad. Sci. U. S. A. 1998;95(26):15718–15723
- . Translating the histone code. Science. 2001;293(5532):1074–1080
- . The cortico-striate projection in the monkey. Brain. 1970;93(3):525–546
- . Bilateral projections from precentral motor cortex to the putamen and other parts of the basal ganglia. An autoradiographic study in Macaca fascicularis. Brain Res. 1975;88(2):195–209
- . Olfactory discrimination learning deficit in heterozygous reeler mice. Brain Res. 2003;971(1):40–46
- . Cortical inhibitory neurons and schizophrenia. Nat. Rev. Neurosci. 2005;6(4):312–324
- . Downregulation of dendritic spine and glutamic acid decarboxylase67 expressions in reelin haploinsufficient heterozygous reeler mouse. Proc. Natl. Acad. Sci. U. S. A. 2001;98(6):3477–3482
- . Histone deacetylase inhibitors decrease reelin promoter methylation in vitro. J. Neurochem. 2005;93(2):483–492
- . DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures. Proc. Natl. Acad. Sci. U. S. A. 2005;102(5):1749–1754
- . Functional anatomy of the basal ganglia. I. The cortico-basal ganglia thalamo-cortical loop. Brain Res. Brain Res. Rev. 1995;20(1):91–127
- . Subnucleus-specific loss of neurons in medial thalamus of schizophrenics. Proc. Natl. Acad. Sci. U. S. A. 2000;97(16):9276–9280
- . Cognitive disruption and altered hippocampus synaptic function in reelin haploinsufficient mice. Neurobiol. Learn. Mem. 2006;85(3):228–242
- . Cytoarchitectonic definition of prefrontal areas in the normal human cortex: I Remapping of areas 9 and 46 using quantitative criteria. Cereb. Cortex. 1995;5(4):307–332
- . Effects of chromatin structure on the enzymatic and DNA binding functions of DNA methyltransferases DNMT1 and Dnmt3a in vitro. Biochem. Biophys. Res. Commun. 2004;322(1):110–118
- . In Patas monkey, glutamic acid decarboxylase-67 and reelin mRNA coexpression varies in a manner dependent on layers and cortical areas. J. Comp. Neurol. 2002;451(3):279–288
- . Mediodorsal thalamic afferents to layer III of the rat prefrontal cortex: synaptic relationships to subclasses of interneurons. J. Comp. Neurol. 2005;490(3):220–238
- Ruzicka, W.B., Zhubi, A., Veldic, M., Grayson, D.R., Costa, E., Guidotti, A., in press. Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection. Mol. Psychiatry.
- . Longitudinal topography and interdigitation of cortico-striatal projections in the rhesus monkey. J. Neurosci. 1985;5(3):776–794
- . The benzamide MS-275 is a potent long-lasting brain region-selective inhibitor of histone deacetylases. Proc. Natl. Acad. Sci. U. S. A. 2006;103(5):1587–1592
- . Frontal-subcortical neuronal circuits and clinical neuropsychiatry: an update. J. Psychosom. Res. 2002;53(2):647–654
- . The basal ganglia: anatomy physiology and pharmacology. Psychiatr. Clin. North Am. 2004;27(4):757–799
- . An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability. Proc. Natl. Acad. Sci. U. S. A. 2002;99(26):17095–17100
- . Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice. Biol. Psychiatry. 2005;57(5):500–509
- . DNA methyltransferase 1 is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains. Proc. Natl. Acad. Sci. U. S. A. 2004;101(1):348–353
- . In psychosis, cortical interneurons overexpress DNA-methyltransferase 1. Proc. Natl. Acad. Sci. U. S. A. 2005;102(6):2152–2157
- . Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia. Arch. Gen. Psychiatry. 2000;57(3):237–245
- . Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder. Arch. Gen. Psychiatry. 2004;61(7):649–657
PII: S0920-9964(06)00493-2
doi: 10.1016/j.schres.2006.11.029
© 2007 Elsevier B.V. All rights reserved.
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Schizophrenia Research
Volume 91, Issue 1
, Pages 51-61
, March 2007
