Schizophrenia Research
Volume 89, Issue 1 , Pages 59-71 , January 2007

Structural analysis of the basal ganglia in schizophrenia

  • Daniel Mamah

      Affiliations

    • Department of Psychiatry, Washington University Medical School, St. Louis, United States
    • Corresponding Author InformationCorresponding author. Department of Psychiatry, Box 8134, Washington University School of Medicine, 660 South Euclid, St. Louis, MO 63110, United States. Tel.: +1 314 362 6954; fax: +1 314 747 2182.
    • ,
  • Lei Wang

      Affiliations

    • Department of Psychiatry, Washington University Medical School, St. Louis, United States
    • ,
  • Deanna Barch

      Affiliations

    • Department of Psychiatry, Washington University Medical School, St. Louis, United States
    • ,
  • Gabriel A. de Erausquin

      Affiliations

    • Department of Psychiatry, Washington University Medical School, St. Louis, United States
    • Department of Neurology, Washington University Medical School, St. Louis, United States
    • ,
  • Mokhtar Gado

      Affiliations

    • Mallinckrodt Department of Radiology, Washington University Medical School, St. Louis, United States
    • ,
  • John G. Csernansky

      Affiliations

    • Department of Psychiatry, Washington University Medical School, St. Louis, United States

Received 4 May 2006 ,Revised 21 August 2006 ,Accepted 23 August 2006.

References 

  1. Andersson C, Hamer RM, Lawler CP, Mailman RB, Lieberman JA. Striatal volume changes in the rat following long-term administration of typical and atypical antipsychotic drugs. Neuropsychopharmacology. 2002;27(2):143–151(Aug)
  2. Andreasen NC, Olsen S. Negative v positive schizophrenia. Arch. Gen. Psychiatry. 1982;39:789–794
  3. Andreasen NC, Arndt S, Alliger R, Miller D, Flaum M. Symptoms of schizophrenia: methods, meanings and mechanisms. Arch. Gen. Psychiatry. 1995;52:341–351
  4. Breier A, Buchanan RW, Elkashef A, Munson RC, Kirkpatrick B, Gellad F. Brain morphology and schizophrenia. A magnetic resonance imaging study of limbic, prefrontal cortex, and caudate structures. Arch. Gen. Psychiatry. 1992;49(12):921–926
  5. Corson PW, Nopoulos P, Andreasen NC, Heckel D, Arndt S. Caudate size in first-episode neuroleptic-naive schizophrenic patients measured using an artificial neural network. Biol. Psychiatry. 1999;46(5):712–720(Sep 1)
  6. Csernansky JG, Joshi S, Wang L, Haller JW, Gado M, Miller JP, et al. Hippocampal morphometry in schizophrenia by high dimensional brain mapping. Proc. Natl. Acad. Sci. U. S. A. 1998;95(19):11406–11411
  7. Csernansky JG, Wang L, Jones D, Rastogi-Cruz D, Posener JA, Hedebrand G, et al. Hippocampal deformities in schizophrenia characterized by high dimensional brain mapping. Am. J. Psychiatry. 2002;159:2000–2006
  8. Csernansky JG, Schindler MK, Splinter NR, Wang L, Gado M, Selemon LD, et al. Abnormalities of thalamic volume and shape in schizophrenia. Am. J. Psychiatry. 2004;161:896–902
  9. DeLong MR. The basal ganglia. In:  Kandel ER,  Schwartz JH,  Jessell TM editor. Principles of Neural Science. McGraw Hill; 2000;p. 853–867
  10. First MB, Spitzer RL, Gibbon M, Williams JBW. In: Structured Clinical Interview for DSM-IV Axis I Disorders, Patient Edition (SCID-P), version 2. New York, New York State Psychiatric Institute, Biometrics Research. 1995;
  11. Gharabawi GM, Bossie CA, Lasser RA, Turkoz I, Rodriguez S, Chouinard G. Abnormal Involuntary Movement Scale (AIMS) and Extrapyramidal Symptom Rating Scale (ESRS): cross-scale comparison in assessing tardive dyskinesia. Schizophr. Res. 2005;77(2–3):119–128(Sep 15)
  12. Grace AA. Gating of information flow within the limbic system and the pathophysiology of schizophrenia. Brain Res. Brain Res. Rev. 2000;31(2–3):330–341(Mar)
  13. Gray JA. Integrating schizophrenia. Schizophr. Bull. 1998;24(2):249–266
  14. Gunduz H, Wu H, Ashtari M, Bogerts B, Crandall D, Robinson DG, et al. Basal ganglia volumes in first-episode schizophrenia and healthy comparison subjects. Biol. Psychiatry. 2002;51(10):801–818(May 15)
  15. Gur RE, Maany V, Mozley PD, Swanson C, Bilker W, Gur RC. Subcortical MRI volumes in neuroleptic-naive and treated patients with schizophrenia. Am. J. Psychiatry. 1998;155(12):1711–1717(Dec)
  16. Hall H, Sedvall G, Magnusson O, Kopp J, Halldin C, Fardel L. Distribution of D1- and D2-dopamine receptors, and dopamine and its metabolites in the human brain. Neuropsychopharmacology. 1994;11:245–256
  17. Haller JW, Banerjee A, Christensen GE, Gado M, Joshi S, Miller MI, et al. Three-dimensional hippocampal MR morphometry by high-dimensional transformation of a neuroanatomic atlas. Radiology. 1997;202:504–510
  18. Joel D. Open interconnected model of basal ganglia-thalamocortical circuitry and its relevance to the clinical syndrome of Huntington's disease. Mov. Disord. 2001;16(3):407–423(May)
  19. Joshi SC, Miller MI, Grenander U. On the geometry and shape of brain sub-manifolds. Int. J. Pattern Recogn. Artif. Intell. 1997;11:1317–1343
  20. Keshavan MS, Rosenberg D, Sweeney JA, Pettegrew JW. Decreased caudate volume in neuroleptic-naive psychotic patients. Am. J. Psychiatry. 1998;155(6):774–778(Jun)
  21. Lang DJ, Kopala LC, Vandorpe RA, Rui Q, Smith GN, Goghari VM, et al. Reduced basal ganglia volumes after switching to olanzapine in chronically treated patients with schizophrenia. Am. J. Psychiatry. 2004;161(10):1829–1836(Oct)
  22. Lehericy S, Ducros M, Van de Moortele PF, Francois C, Thivard L, Poupon C, et al. Diffusion tensor fiber tracking shows distinct corticostriatal circuits in humans. Ann. Neurol. 2004;55(4):522–529(Apr)
  23. Levy R, Friedman HR, Davachi L, Goldman Rakic PS. Differential activation of the caudate nucleus in primates performing spatial and nonspatial working memory tasks. J. Neurosci. 1997;17:3870–3882
  24. Manoach DS, Gollub RL, Benson ES, Searly MM, Goff DC, Halpern E, et al. Schizophrenic subjects show aberrant fMRI activation of dorsolateral prefrontal cortex and basal ganglia during working memory performance. Biol. Psychiatry. 2000;48(2):99–109(Jul 15)
  25. McCarley RW, Wible CG, Frumin M, Hirayasu Y, Levitt JJ, Fischer IA, et al. MRI anatomy of schizophrenia. Biol. Psychiatry. 1999;45(9):1099–1119(May 1)
  26. Mendez MF, Adams NL, Lewandowski KS. Neurobehavioral changes associated with caudate lesions. Neurology. 1989;39(3):349–354
  27. Menon V, Anagnoson RT, Glover GH, Pfefferbaum A. Functional magnetic resonance imaging evidence for disrupted basal ganglia function in schizophrenia. Am. J. Psychiatry. 2001;158(4):646–649(Apr)
  28. Miller M, Banerjee A, Christensen G, Joshi S, Khaneja N, Grenander U, et al. Statistical methods in computational anatomy. Stat. Methods Med. Res. 1997;6(3):267–299(Sep)
  29. Nuechterlein KH, Barch DM, Gold JM, Goldberg TE, Green MF, Heaton RK. Identification of separable cognitive factors in schizophrenia. Schizophr. Res. 2004;72:29–39
  30. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neurospcyhologia. 1971;9:97–113
  31. Pardo JV, Fox PT, Raichle ME. Localization of a human system for sustained attention by positron emission tomography. Nature. 1991;349(6304):61–64(Jan 3)
  32. Parent A, Hazrati LN. Functional anatomy of the basal ganglia: I. The cortico-basal ganglia-talamo-cortical loop. Brain Res. Brain Res. Rev. 1995;20:91–127
  33. Rosa-Neto P, Doudet DJ, Cumming P. Gradients of dopamine D1- and D2/3-binding sites in the basal ganglia of pig and monkey measured by PET. Neuroimage. 2004;22:1076–1083
  34. Shihabuddin L, Buchsbaum MS, Hazlett EA, Haznedar MM, Harvey PD, Newman A, et al. Dorsal striatal size, shape, and metabolic rate in never-medicated and previously medicated schizophrenics performing a verbal learning task. Arch. Gen. Psychiatry. 1998;5593:235–243(Mar)
  35. Staal WG, Hulshoff Pol HE, Schnack HG, Hoogendoorn ML, Jellema K, Kahn RS. Structural brain abnormalities in patients with schizophrenia and their healthy siblings. Am. J. Psychiatry. 2000;157(3):416–421(Mar)
  36. Suwa H, Matsushima E, Ohta K, Mori K. Attention disorders in schizophrenia. Psychiatry Clin. Neurosci. 2004;58(3):249–256(Jun)
  37. Swayze VW, Andreasen NC, Alliger RJ, Yuh WT, Ehrhardt JC. Subcortical and temporal structures in affective disorder and schizophrenia: a magnetic resonance imaging study. Biol. Psychiatry. 1992;31:221–240
  38. Vankatesan R, Haacke EM. Role of high resolution in magnetic resonance (MR) imaging: applications of MR angiography, intracranial T1-weighted imaging, and image interpolation. Int. J. Imaging Syst. Technol. 1997;8:529–543
  39. Wang L, Joshi SC, Miller MI, Grenander U, Csernansky JG. Statistical analysis of hippocampal asymmetry. Neuroimage. 2001;14:531–545
  40. Wang, L., Lee, D.Y., Bailey, E., Hartlein, J.M., Gado, M.H., Miller, M.I., Black, K.J., in press. Validity of large-deformation high dimensional brain mapping of the basal ganglia in adults with Tourette syndrome. Psychiatry Research. Neuroimaging.
  41. Zgaljardic DJ, Borod JC, Foldi NS, Mattis P. A review of the cognitive and behavioral sequelae of Parkinson's disease: relationship to frontostriatal circuitry. Cogn. Behav. Neurol. 2003;16(4):193–210(Dec)

PII: S0920-9964(06)00386-0

doi: 10.1016/j.schres.2006.08.031

Schizophrenia Research
Volume 89, Issue 1 , Pages 59-71 , January 2007

Article Tools

* Image Usage & Resolution