Schizophrenia Research
Volume 88, Issue 1 , Pages 96-101 , December 2006

A population based elaboration of the role of age of onset on the course of schizophrenia

  • Jonathan Rabinowitz

      Affiliations

    • Bar Ilan University, Ramat Gan, Israel
    • Corresponding Author InformationCorresponding author. Tel.: +972 9 748 3679; fax: +972 9 740 1318.
  • ,
  • Stephen Z. Levine

      Affiliations

    • Bar Ilan University, Ramat Gan, Israel
  • ,
  • Heinz Häfner

      Affiliations

    • Central Institute of Mental Health, Mannheim, Germany

Received 12 May 2006 ,Revised 22 June 2006 ,Accepted 17 July 2006.

References 

  1. AbdelMalik P, Husted J, Chow EW, et al. Childhood head injury and expression of schizophrenia in multiply affected families. Arch. Gen. Psychiatry. 2003;60(3):231–236
  2. Aleman A, Kahn RS, Selten JP. Sex differences in the risk of schizophrenia: evidence from meta-analysis. Arch. Gen. Psychiatry. 2003;60(6):565–571
  3. Angermeyer MC, Kuhn L. Gender differences in age at onset of schizophrenia. An overview. Eur. Arch. Psychiatr. Neurol. Sci. 1988;237(6):351–364
  4. Angermeyer MC, Kuhn L, Goldstein JM. Gender and the course of schizophrenia: differences in treated outcomes. Schizophr. Bull. 1990;16(2):293–307
  5. Breiman L, Friedman JH. Estimating optimal transformations for multiple regression and correlations (with discussion). J. Am. Stat. Assoc. 1985;80:580–619
  6. Byrne M, Agerbo E, Mortensen PB. Family history of psychiatric disorders and age at first contact in schizophrenia: an epidemiological study. Br. J. Psychiatr., Suppl. 2002;43:s19–s25
  7. DeLisi LE. The significance of age of onset for schizophrenia. Schizophr. Bull. 1992;18(2):209–215
  8. DeLisi LE, Boccio AM, Riordan H, et al. Familial thyroid disease and delayed language development in first admission patients with schizophrenia. Psychiatry Res. 1991;38(1):39–50
  9. Eaton WW, Mortensen PB, Herrman H, et al. Long-term course of hospitalization for schizophrenia. Part I. Risk for rehospitalization. Schizophr. Bull. 1992;18(2):217–228
  10. Häfner H. Onset and early course as determinants of the further course of schizophrenia. Acta Psychiatr. Scand., Suppl. 2000;407:44–48
  11. Häfner H, Loffler W, Maurer K, et al. Depression, negative symptoms, social stagnation and social decline in the early course of schizophrenia. Acta Psychiatr. Scand. 1999;100(2):105–118
  12. Hollis C. Adolescent schizophrenia. Adv. Psychiatr. Treat. 2000;6:83–92
  13. Hollis C. Adult outcomes of child- and adolescent-onset schizophrenia: diagnostic stability and predictive validity. Am. J. Psychiatry. 2000;157(10):1652–1659
  14. Hothorn, T., Hornik, K. Krull, A., in press. Unbiased recursive partitioning: a conditional inference framework. J Comp Graph Stat.
  15. Ihaka R, Gentleman R. R: a language for data analysis and graphics. J. Comput. Graph. Stat. 1996;5(3):299–314
  16. Jablensky A. Epidemiology of schizophrenia: the global burden of disease and disability. Eur. Arch. Psychiatry Clin. Neurosci. 2000;250(6):274–285
  17. Jeste DV, Harris MJ, Krull A, et al. Clinical and neuropsychological characteristics of patients with late-onset schizophrenia. Am. J. Psychiatry. 1995;152(5):722–730
  18. Kuo CJ, Tsai SY, Lo CH, et al. Risk factors for completed suicide in schizophrenia. J. Clin. Psychiatry. 2005;66(5):579–585
  19. Lay B, Blanz B, Hartmann M, et al. The psychosocial outcome of adolescent-onset schizophrenia: a 12-year followup. Schizophr. Bull. 2000;26(4):801–816
  20. Leung A, Chue P. Sex differences in schizophrenia, a review of the literature. Acta Psychiatr. Scand., Suppl. 2000;401:3–38
  21. Loranger AW. Sex difference in age at onset of schizophrenia. Arch. Gen. Psychiatry. 1984;41(2):157–161
  22. Mark M, Rabinowitz J, Feldman D. Revamping mental health care in Israel: from the Netanyahu Commission to National Health Insurance Law. Soc. Work Health Care. 1997;25(3):119–129
  23. Meltzer HY, Rabinowitz J, Lee MA, et al. Age at onset and gender of schizophrenic patients in relation to neuroleptic resistance. Am. J. Psychiatry. 1997;154(4):475–482
  24. Mueser KT, McGurk SR. Schizophrenia. Lancet. 2004;363(9426):2063–2072
  25. Nimgaonkar VL, Wessely S, Tune LE, et al. Response to drugs in schizophrenia: the influence of family history, obstetric complications and ventricular enlargement. Psychol. Med. 1988;18(3):583–592
  26. Olesen AV, Mortensen PB. Readmission risk in schizophrenia: selection explains previous findings of a progressive course of disorder. Psychol. Med. 2002;32(7):1301–1307
  27. Pearlson GD, Kreger L, Rabins PV, et al. A chart review study of late-onset and early-onset schizophrenia. Am. J. Psychiatry. 1989;146(12):1568–1574
  28. Rabinowitz J, Slyuzberg M, Ritsner M, et al. Changes in diagnosis in a 9-year national longitudinal sample. Compr. Psychiatry. 1994;35(5):361–365
  29. Rapoport . Childhood Onset of “Adult” Pathology: Clinical and Research Advances. Washington, DC: American Psychiatric Press; 2000;
  30. Schurhoff F, Golmard JL, Szoke A, et al. Admixture analysis of age at onset in schizophrenia. Schizophr. Res. 2004;71(1):35–41
  31. Subotnik KL, Nuechterlein KH, Irzhevsky V, et al. Is unawareness of psychotic disorder a neurocognitive or psychological defensiveness problem?. Schizophr. Res. 2005;75(2–3):147–157
  32. Suvisaari JM, Haukka J, Tanskanen A, et al. Age at onset and outcome in schizophrenia are related to the degree of familial loading. Br. J. Psychiatry. 1998;173:494–500
  33. Weiser M, Kanyas K, Malaspina D, et al. Sensitivity of ICD-10 diagnosis of psychotic disorders in the Israeli National Hospitalization Registry compared with RDC diagnoses based on SADS-L. Compr. Psychiatry. 2005;46(1):38–42

PII: S0920-9964(06)00320-3

doi: 10.1016/j.schres.2006.07.007

Schizophrenia Research
Volume 88, Issue 1 , Pages 96-101 , December 2006