Schizophrenia Research
Volume 80, Issue 2 , Pages 197-201 , 15 December 2005

Confirmation of a relationship between reduced auditory P300 amplitude and thought disorder in schizophrenia

  • Kenji Kirihara

      Affiliations

    • Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyoku, Tokyo 113-8655, Japan
    • Corresponding Author InformationCorresponding authors. Kirihara is to be contacted at Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyoku, Tokyo 113-8655, Japan. Tel.: +81 3 5800 9263; fax: +81 3 5800 6894.
    • ,
  • Tsuyoshi Araki

      Affiliations

    • Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyoku, Tokyo 113-8655, Japan
    • ,
  • Kiyoto Kasai

      Affiliations

    • Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyoku, Tokyo 113-8655, Japan
    • Corresponding Author InformationCorresponding authors. Kirihara is to be contacted at Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyoku, Tokyo 113-8655, Japan. Tel.: +81 3 5800 9263; fax: +81 3 5800 6894.
    • ,
  • Keiko Maeda

      Affiliations

    • Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyoku, Tokyo 113-8655, Japan
    • ,
  • Akinobu Hata

      Affiliations

    • Fukushima Prefectural Mental Health and Welfare Centre, 8-30 Oyamacho, Fukushimashi, Fukushima 960-8012, Japan
    • ,
  • Miki Uetsuki

      Affiliations

    • Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyoku, Tokyo 113-8655, Japan
    • ,
  • Hidenori Yamasue

      Affiliations

    • Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyoku, Tokyo 113-8655, Japan
    • ,
  • Mark A. Rogers

      Affiliations

    • Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyoku, Tokyo 113-8655, Japan
    • Department of Psychology, Monash University, Clayton 3168, Vicotoria, Australia
    • ,
  • Nobumasa Kato

      Affiliations

    • Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyoku, Tokyo 113-8655, Japan
    • ,
  • Akira Iwanami

      Affiliations

    • Department of Medical Technology, Aino University, 4-5-4 Higashiohta, Ibaraki, Osaka 567-0012, Japan

Received 14 May 2005 ,Revised 3 August 2005 ,Accepted 3 August 2005.

References 

  1. American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders. 4th ed.. Washington, DC: APA; 1994;
  2. Andreasen NC. Scale for the assessment of thought, language, and communication (TLC). Scihzophr. Bull. 1986;12:473–483
  3. Blackwood D, Whalley L, Christie J, Blackburn I, St. Clair D, McInnes A. Changes in auditory P3 event-related potential in schizophrenia and depression. Br. J. Psychiatry. 1987;150:154–160
  4. Bleuler, E., 1911/1956. Dementia Praecox or the Group of Schizophrenias. International Universities Press, New York.
  5. Ford JM, Pfefferbaum A, Roth W. P3 and schizophrenia. Ann. N. Y. Acad. Sci. 1992;658:146–162
  6. Ford JM, Mathalon DH, Marsh L, Faustman W, Harris D, Hoff A, et al. P300 amplitude is related to clinical state in severely and moderately ill schizophrenics. Biol. Psychiatry. 1999;46:94–101
  7. Frodl T, Meisenzahl EM, Muller D, Holder J, Juckel G, Moller HJ, et al. P300 subcomponents and clinical symptoms in schizophrenia. Int. J. Psychophysiol. 2002;43:237–246
  8. Hata A, Iwanami A, Nakagome K, Niwa S. Scoring manual for thought disorder index. In: Thought Disorder: Assessment and Background. Tokyo: Shinko-Igaku Publishers; 2002;p. 136–178(in Japanese)
  9. Higashima M, Urata K, Kawasaki Y, Maeda Y, Sakai N, Mizukoshi C, et al. P300 and the thought disorder factor extracted by factor-analytic procedures in schizophrenia. Biol. Psychiatry. 1998;44:115–120
  10. Inagaki A, Inada T, Fujii Y, Yagi G. Dose equivalence of neuroleptics. In:  Inagaki A,  Inada T,  Fujii Y,  Yagi G,  Yoshio T,  Nakamura H,  Yamauchi T editor. Dose Equivalence of Psychotropic Drugs. Tokyo: Seiwa Publishers; 1999;p. 11–60(in Japanese)
  11. Iwanami A, Okajima Y, Kuwakado D, Isono H, Kasai K, Hata A, et al. Event-related potentials and thought disorder in schizophrenia. Schizophr. Res. 2000;42:187–191
  12. Johnston MH, Holzman PS. Assessing Schizophrenic Thinking: A Clinical and Research Instrument for Measuring Thought Disorder. San Francisco: Jossey-Bass; 1979;
  13. Juckel G, Muller-Schubert A, Gaebel W, Hegerl U. Residual symptoms and P300 in schizophrenic outpatients. Psychiatry Res. 1996;66:23–32
  14. Kay SR, Fisszbein A, Opler LA. The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr. Bull. 1987;13:261–276
  15. Marengo JT, Harrow M, Latin Kettering L, Wilson A. Evaluating bizarre-idiosyncratic thinking: a comprehensive index of positive thought disorder. Schizophr. Bull. 1986;12:497–511
  16. McCarley RW, Faux SF, Shenton ME, Nestor PG, Adams J. Event-related potentials in schizophrenia — their biological and clinical correlates and a new model of schizophrenic pathophysiology. Schizophr. Res. 1991;4:209–231
  17. McCarley RW, Shenton ME, O'Donnell BF, Faux SF, Kikinis R, Nestor PG, et al. Auditory P300 abnormalities and left posterior superior temporal gyrus volume reduction in schizophrenia. Arch. Gen. Psychiatry. 1993;50:190–197
  18. Pfefferbaum A, Ford JM, White P, Roth WT. P3 in schizophrenia is affected by stimulus modality, response requirements, medication status and negative symptoms. Arch. Gen. Psychiatry. 1989;46:1035–1046
  19. Shenton ME, Kikinis R, Jolesz FA, Pollak SD, LeMay M, Wible CG, et al. Abnormalities of the left temporal lobe and thought disorder in schizophrenia: a quantitative magnetic resonance imaging study. N. Engl. J. Med. 1992;327:604–612
  20. Solovay MR, Shenton ME, Gasperetti C, Coleman M, Kestnbaum E, Carpenter JT, et al. Scoring manual for the thought disorder index. Schizophr. Bull. 1986;12:483–496
  21. Solovay MR, Shenton ME, Holzman PS. Comparative studies of thought disorder: I. Mania and schizophrenia. Arch. Gen. Psychiatry. 1987;44:13–20
  22. Ward PB, Catts SV, Fox AM, Michie PT, McConaghy N. Auditory selective attention and event-related potentials in schizophrenia. Br. J. Psychiatry. 1991;158:534–539

PII: S0920-9964(05)00359-2

doi: 10.1016/j.schres.2005.08.003

Schizophrenia Research
Volume 80, Issue 2 , Pages 197-201 , 15 December 2005

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