Schizophrenia Research
Volume 78, Issue 2 , Pages 127-130 , 15 October 2005

No association of haplotype-tagging SNPs in TRAR4 with schizophrenia in Japanese patients

  • Masashi Ikeda

      Affiliations

    • Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan
    • Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya 466-8850, Japan
    • Corresponding Author InformationCorresponding author. Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan. Tel.: +81 562 93 9250; fax: +81 562 93 1831.
    • ,
  • Nakao Iwata

      Affiliations

    • Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan
    • ,
  • Tatsuyo Suzuki

      Affiliations

    • Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan
    • ,
  • Tsuyoshi Kitajima

      Affiliations

    • Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan
    • ,
  • Yoshio Yamanouchi

      Affiliations

    • Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan
    • ,
  • Yoko Kinoshita

      Affiliations

    • Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan
    • ,
  • Toshiya Inada

      Affiliations

    • Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya 466-8850, Japan
    • ,
  • Norio Ozaki

      Affiliations

    • Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya 466-8850, Japan

Received 27 April 2005 ,Revised 2 May 2005 ,Accepted 4 May 2005.

References 

  1. Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21:263–265
  2. Duan J, Martinez M, Sanders AR, Hou C, Saitou N, Kitano T, et al. Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia. Am. J. Hum. Genet. 2004;75:624–638
  3. Ikeda M, Iwata N, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, et al. No association of GSK3beta gene (GSK3B) with Japanese schizophrenia. Am. J. Med. Genet., B Neuropsychiatr. Genet. 2005;134:90–92
  4. Ke X, Cardon LR. Efficient selective screening of haplotype tag SNPs. Bioinformatics. 2003;19:287–288
  5. Nyholt DR. A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am. J. Hum. Genet. 2004;74:765–769
  6. Ohashi J, Yamamoto S, Tsuchiya N, Hatta Y, Komata T, Matsushita M, et al. Comparison of statistical power between 2*2 allele frequency and allele positivity tables in case–control studies of complex disease genes. Ann. Hum. Genet. 2001;65:197–206
  7. Parker EM, Cubeddu LX. Effects of d-amphetamine and dopamine synthesis inhibitors on dopamine and acetylcholine neurotransmission in the striatum: I. Release in the absence of vesicular transmitter stores. J. Pharmacol. Exp. Ther. 1986;237:179–192
  8. Pritchard JK. Are rare variants responsible for susceptibility to complex diseases?. Am. J. Hum. Genet. 2001;69:124–137
  9. Suzuki T, Iwata N, Kitamura Y, Kitajima T, Yamanouchi Y, Ikeda M, et al. Association of a haplotype in the serotonin 5-HT4 receptor gene (HTR4) with Japanese schizophrenia. Am. J. Med. Genet. 2003;121B:7–13

PII: S0920-9964(05)00192-1

doi: 10.1016/j.schres.2005.05.002

Schizophrenia Research
Volume 78, Issue 2 , Pages 127-130 , 15 October 2005

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