Schizophrenia Research
Volume 77, Issue 2 , Pages 189-199 , 15 September 2005

Contrasting loxapine to its isomer isoloxapine—the critical role of in vivo D2 blockade in determining atypicality

  • Sridhar Natesan

      Affiliations

    • Schizophrenia-PET program, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada, M5T 1R8
  • ,
  • Suzi VanderSpek

      Affiliations

    • Schizophrenia-PET program, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada, M5T 1R8
  • ,
  • José N. Nobrega

      Affiliations

    • Neuroimaging Research Section, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada, M5T 1R8
    • Department of Pharmacology, 1 King's College Circle, University of Toronto, Toronto, Ontario, Canada, M5S 1A8
  • ,
  • Robert A. McClelland

      Affiliations

    • Department of Chemistry, 80 St. George Street, University of Toronto, Toronto, Ontario, Canada, M5S 3H6
  • ,
  • Shitij Kapur

      Affiliations

    • Schizophrenia-PET program, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada, M5T 1R8
    • Department of Psychiatry, University of Toronto, 8th Floor, 250 College Street, Toronto, Ontario, Canada, M5T 1R8
    • Corresponding Author InformationCorresponding author. Centre for Addiction and Mental Health, ARF Site, 33 Russell Street, Toronto, Ontario, Canada, M5S 2S1. Tel.: +1 416 979 6890; fax: +1 416 260 4206.

Received 3 December 2004 ,Revised 1 March 2005 ,Accepted 14 March 2005.

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PII: S0920-9964(05)00119-2

doi: 10.1016/j.schres.2005.03.009

Schizophrenia Research
Volume 77, Issue 2 , Pages 189-199 , 15 September 2005