Schizophrenia Research
Volume 76, Issue 1 , Pages 55-65 , 1 July 2005

Dysfunction of early-stage visual processing in schizophrenia: harmonic analysis

  • Dongsoo Kim

      Affiliations

    • Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY, USA
  • ,
  • Vance Zemon

      Affiliations

    • Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY, USA
    • Ferkauf Graduate School of Psychology, Yeshiva University, 1300 Morris Park Ave. Bronx, NY, USA
  • ,
  • Alice Saperstein

      Affiliations

    • Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY, USA
  • ,
  • Pamela D. Butler

      Affiliations

    • Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY, USA
    • Department of Psychiatry, New York University School of Medicine, New York, NY, USA
    • Corresponding Author InformationCorresponding author. Cognitive Neuroscience and Schizophrenia, Nathan S. Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA. Tel.: +1 845 398 6537; fax: +1 845 398 6545.
  • ,
  • Daniel C. Javitt

      Affiliations

    • Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY, USA
    • Department of Psychiatry, New York University School of Medicine, New York, NY, USA

Received 10 November 2003 ,Revised 11 October 2004 ,Accepted 13 October 2004.

References 

  1. Adler LE, Freedman R, Ross RG, Olincy A, Waldo MC. Elementary phenotypes in the neurobiological and genetic study of schizophrenia. Biol. Psychiatry. 1999;46:8–18
  2. Bodis-Wollner I, Tzelepi A. The push–pull action of dopamine on spatial tuning of the monkey retina: the effects of dopaminergic deficiency and selective D1 and D2 receptor ligands on the pattern electroretinogram. Vision Res. 1998;38:1479–1487
  3. Braff DL, Saccuzzo DP. Effect of antipsychotic medication on speed of information processing in schizophrenic patients. Am. J. Psychiatry. 1982;139:1127–1130
  4. Braff D, Saccuzzo D, Geyer M. Information processing dysfunctions in schizophrenia: studies of visual backward masking, sensorimotor gating, and habituation. In:  Steinhauer S,  Gruzelier J,  Zubin J editor. Handbook of Schizophrenia. vol. 5:New York: Elsevier; 1991;p. 303–334
  5. Braus DF, Weber-Fahr W, Tost H, Ruf M, Henn FA. Sensory information processing in neuroleptic-naive first-episode schizophrenic patients: a functional magnetic resonance imaging study. Arch. Gen. Psychiatry. 2002;59:696–701
  6. Brenner CA, Wilt MA, Lysaker PH, Koyfman A, O'Donnell BF. Psychometrically matched visual-processing tasks in schizophrenia spectrum disorders. J. Abnorm. Psychology. 2003;112:28–37
  7. Butler PD, Harkavy-Friedman JM, Amador XF, Gorman JM. Backward masking in schizophrenia: relationship to medication status, neuropsychological functioning, and dopamine metabolism. Biol. Psychiatry. 1996;40:295–298
  8. Butler PD, Schechter I, Zemon V, Schwartz SG, Greenstein VC, Gordon J, et al. Dysfunction of early-stage visual processing in schizophrenia. Am. J. Psychiatry. 2001;158:1126–1133
  9. Butler PD, DeSanti LA, Maddox J, Harkavy-Friedman JM, Amador XF, Goetz RR, et al. Visual backward-masking deficits in schizophrenia: relationship to visual pathway function and symptomatology. Schizophr. Res. 2002;59:199–209
  10. Cadenhead KS, Serper Y, Braff DL. Transient versus sustained visual channels in the visual backward masking deficits of schizophrenia patients. Biol. Psychiatry. 1998;43:132–138
  11. Carandini M, Heeger DJ. Summation and division by neurons in primate visual cortex. Science. 1994;264:1333–1336
  12. Chen Y, Levy DL, Nakayama K, Matthysse S, Palafox G, Holzman PS. Dependence of impaired eye tracking on deficient velocity discrimination in schizophrenia. Arch. Gen. Psychiatry. 1999;56:155–161
  13. Chen Y, Nakayama K, Levy D, Matthysse S, Holzman P. Processing of global, but not local, motion direction is deficient in schizophrenia. Schizophr. Res. 2003;61:215–227
  14. Doniger GM, Foxe JJ, Murray MA, Higgins BA, Schroeder CE, Javitt DC. Activation timecourse of ventral visual stream object-recognition areas: high density electrical imaging of perceptual closure processes. J. Cogn. Neurosci. 2000;12:615–621
  15. Doniger GM, Foxe JJ, Murray MM, Higgins BA, Javitt DC. Impaired visual object recognition and dorsal/ventral stream interaction in schizophrenia. Arch. Gen. Psychiatry. 2002;59:1011–1020
  16. Foxe JJ, Doniger GM, Javitt DC. Early visual processing deficits in schizophrenia: impaired P1 generation revealed by high-density electrical mapping. NeuroReport. 2001;12:3815–3820
  17. Gilbert CD, Wiesel TN. Columnar specificity of intrinsic horizontal and corticocortical connections in cat visual cortex. J. Neurosci. 1989;9:2432–2442
  18. Goldberg T, Gold J. Neurocognitive functioning in patients with schizophrenia: an overview. In:  Bloom FE,  Kupfer D editor. Psychopharmacology: The Fourth Generation of Progress. New York: Raven Press; 1995;p. 1245–1257
  19. Goldman-Rakic PS. Working memory dysfunction in schizophrenia. J. Neuropsychiatry Clin. Neurosci. 1994;6:348–357
  20. Green M. Schizophrenia from a Neurocognitive Perspective. Boston: Allyn and Bacon; 1998;
  21. Green MF, Nuechterlein KH, Mintz J. Backward masking in schizophrenia and mania: II. Specifying the visual channels. Arch. Gen. Psychiatry. 1994;51:945–951
  22. Green MF, Nuechterlein KH, Breitmeyer B, Mintz J. Backward masking in unmedicated schizophrenic patients in psychotic remission: possible reflection of aberrant cortical oscillation. Am. J. Psychiatry. 1999;156:1367–1373
  23. Grose-Fifer J, Zemon V, Gordon J. Temporal tuning and the development of lateral interactions in the human visual system. Invest. Ophthalmol. Visual. Sci. 1994;35:2999–3010
  24. Hirsch JA, Gilbert CD. Synaptic physiology of horizontal connections in the cat's visual cortex. J. Neurosci. 1991;11:1800–1809
  25. Hollingshead AB, Redlich FL. Social Class and Mental Illness. New York: Wiley; 1958;
  26. Javitt DC, Liederman E, Cienfuegos A, Shelley AM. Panmodal processing imprecision as a basis for dysfunction of transient memory storage systems in schizophrenia. Schizophr. Bull. 1999;25:763–775
  27. Jibiki I, Kurokawa K, Fukushima T, Yamaguchi N. Acutely administered haloperidol has little effect on steady-state visual evoked potentials from pattern-reversal stimulations in treated schizophrenics. Jpn. J. Psychiatry Neurol. 1993;47:51–55
  28. Kaplan E. The receptive field structure of retinal ganglion cells in cat and monkey. In:  Leventhal AG editors. Vision and Visual Dysfunction. Boston: CRC Press; 1991;p. 10–40
  29. Keri S, Kelemen O, Benedek G, Janka Z. Vernier threshold in patients with schizophrenia and in their unaffected siblings. Neuropsychology. 2004;18:537–542
  30. Lamme VA, Roelfsema PR. The distinct modes of vision offered by feedforward and recurrent processing. Trends Neurosci. 2000;23:571–579
  31. Li CS. Impaired detection of visual motion in schizophrenia patients. Prog. Neuro-psychopharmacol. Biol. Psychiatry. 2002;26:929–934
  32. Logothetis NK. The neural basis of the blood-oxygen-level-dependent functional magnetic resonance imaging signal. Philos. Trans. R. Soc. Lond., B Biol. Sci. 2002;357:1003–1037
  33. McKeefry DJ, Russell MH, Murray IJ, Kulikowski JJ. Amplitude and phase variations of harmonic components in human achromatic and chromatic visual evoked potentials. Vis. Neurosci. 1996;13:639–653
  34. McKeefry DJ, Watson JD, Frackowiak RS, Fong K, Zeki S. The activity in human areas V1/V2, V3, and V5 during the perception of coherent and incoherent motion. NeuroImage. 1997;5:1–12
  35. Murray I, MacCana F, Kulikowski JJ. Contribution of two movement detecting mechanisms to central and peripheral vision. Vision Res. 1983;23:151–159
  36. O'Donnell BF, Swearer JM, Smith LT, Nestor PG, Shenton ME, McCarley RW. Selective deficits in visual perception and recognition in schizophrenia. Am. J. Psychiatry. 1996;153:687–692
  37. Regan D. Human Brain Electrophysiology: Evoked Potentials and Evoked Magnetic Fields in Science and Medicine. New York: Elsevier; 1989;
  38. Saccuzzo DP, Braff DL. Information-processing abnormalities: trait- and state-dependent components. Schizophr. Bull. 1986;12:447–459
  39. Schechter I, Butler PD, Silipo G, Zemon V, Javitt DC. Magnocellular and parvocellular contributions to backward masking dysfunction in schizophrenia. Schizophr. Res. 2003;1902:1–11
  40. Schroeder CE, Mehta AD, Givre SJ. A spatiotemporal profile of visual system activation revealed by current source density analysis in the awake macaque. Cereb. Cortex. 1998;8:575–592
  41. Schwartz BD, Maron BA, Evans WJ, Winstead DK. High velocity transient visual processing deficits diminish ability of patients with schizophrenia to recognize objects. Neuropsychiatry Neuropsychol. Behav. Neurol. 1999;12:170–177
  42. Slaghuis WL, Bakker VJ. Forward and backward visual masking of contour by light in positive- and negative-symptom schizophrenia. J. Abnorm. Psychology. 1995;104:41–54
  43. Slaghuis WL, Curran CE. Spatial frequency masking in positive- and negative-symptom schizophrenia. J. Abnorm. Psychology. 1999;108:42–50
  44. Slaghuis WL, Thompson AK. The effect of peripheral visual motion on focal contrast sensitivity in positive- and negative-symptom schizophrenia. Neuropsychologia. 2003;41:968–980
  45. Sokol S, Zemon V, Moskowitz A. Development of lateral interactions in the infant visual system. Vis. Neurosci. 1992;8:3–8
  46. Somogyi P, Freund TF, Cowey A. The axo-axonic interneuron in the cerebral cortex of the rat, cat and monkey. Neuroscience. 1982;7:2577–2607
  47. Steinman BA, Steinman SB, Lehmkuhle S. Transient visual attention is dominated by the magnocellular stream. Vision Res. 1997;37:17–23
  48. Tootell RB, Hadjikhani NK, Vanduffel W, Liu AK, Mendola JD, Sereno MI, et al. Functional analysis of primary visual cortex (V1) in humans. Proc. Natl. Acad. Sci. U. S. A. 1998;95:811–817
  49. Ungerleider L, Mishkin M. Two cortical visual system. In:  Ingle D,  Goodale MA,  Mansfield RJW editor. Analysis of Visual Behavior. Cambridge, MA: MIT Press; 1982;p. 549–580
  50. Victor JD, Zemon V. The human visual evoked potential: analysis of components due to elementary and complex aspects of form. Vision Res. 1985;25:1829–1842
  51. Weinberger DR, Gallhofer B. Cognitive function in schizophrenia. Int. Clin. Psychopharmacol. 1997;12(Suppl. 4):S29–S36
  52. Zemon V, Ratliff F. Visual evoked potentials: evidence for lateral interactions. Proc. Natl. Acad. Sci. U. S. A. 1982;79:5723–5726
  53. Zemon V, Ratliff F. Intermodulation components of the visual evoked potential: responses to lateral and superimposed stimuli. Biol. Cybern. 1984;50:401–408
  54. Zemon V, Kaplan E, Ratliff R. The role of GABA-mediated intracortical inhibition in the generation of visual evoked potentials. In:  Cracco R,  Bodis-Wollner I editor. Evoked Potentials: Frontiers of Clinical Neuroscience. Vol. 3:New York: Alan R. Liss, INC.; 1986;p. 287–295
  55. Zemon V, Victor JD, Ratliff F. Functional subsystems in the visual pathways of humans characterized using evoked potentials. In:  Cracco R,  Bodis-Wollner I editor. Evoked Potentials: Frontiers of Clinical Neuroscience. vol. 3:New York: Alan R. Liss; 1986;p. 203–210
  56. Zemon V, Buckley S, Fitzgerald K, Gordon J, Hartmann E, Meyer A. Objective determination of signal from noise in swept-parameter transient visual evoked potentials (VEPs). Invest. Ophthalmol. Visual. Sci. 1999;40/4:S824

PII: S0920-9964(04)00397-4

doi: 10.1016/j.schres.2004.10.011

Schizophrenia Research
Volume 76, Issue 1 , Pages 55-65 , 1 July 2005