« Previous
Next »
Schizophrenia Research
Volume 67, Issue 1
, Pages 95-106
, 1 March 2004
Epigenetic studies of genomic retroelements in major psychosis
References
- . Molecular characterization of a Y;15 translocation segregating in a family. Hum. Genet. 1988;79:29–35
- . Characterization of densin-180, a new brain-specific synaptic protein of the O-sialoglycoprotein family. J. Neurosci. 1996;16:6839–6852
- . Genetic insights into schizophrenia. Can. J. Psychiatry. 2001;46:131–137
- . Identification of an interstitial deletion in an adult female with schizophrenia, mental retardation, and dysmorphic features: further support for a putative schizophrenia-susceptibility locus at 5q21–23.1. Am. J. Hum. Genet. 1997;61:1450–1454
- . Susceptibility loci for bipolar disorder: overlap with inherited vulnerability to schizophrenia. Biol. Psychiatry. 2000;47:245–251
- . Are schizophrenic and bipolar disorders related? A review of family and molecular studies. Biol. Psychiatry. 2000;48:531–538
- . Review of bipolar molecular linkage and association studies. Curr. Psychiatry Rep. 2002;4:124–129
-
.
DNA methyltransferases in mammalian development and genome defense.
In: Epigenetic Mechanisms of Gene Regulation. Cold Spring Harbor: Cold Spring Harbor Laboratory Press; 1996;p. 61–76
- . Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21–q22. Science. 2000;288:678–682
- . Genomewide multipoint linkage analysis of seven extended Palauan pedigrees with schizophrenia, by a Markov-chain Monte Carlo method. Am. J. Hum. Genet. 2001;69:1278–1289
- . A twin study of genetic relationships between psychotic symptoms. Am. J. Psychiatry. 2002;159:539–545
- . Leukemia inhibitory factor maintains choline acetyltransferase expression in vivo. NeuroReport. 1998;9:363–366
- . Report of the Chromosome 5 Workshop of the Sixth World Congress on Psychiatric Genetics. Am. J. Med. Genet. 1999;88:229–232
- . A genome-wide scan for linkage to chromosomal regions in 382 sibling pairs with schizophrenia or schizoaffective disorder. Am. J. Psychiatry. 2002;159:803–812
- . Affected-sib-pair analyses reveal support of prior evidence for a susceptibility locus for bipolar disorder, on 21q. Am. J. Hum. Genet. 1996;58:1279–1285
- . A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2. Proc. Natl. Acad. Sci. U. S. A. 1999;96:5604–5609
- . An upstream repressor element plays a role in Igf2 imprinting. EMBO J. 2001;20:3518–3525
-
.
Effect of DNA methylation and the binding of vertebrate and plant proteins to DNA.
In:
Jost J, Saluz P editor. DNA Methylation: Molecular Biology and Biological Significance. Basel, Switzerland: Birkhauser; 1993;p. 145–168
- A contiguous clone map over 3 Mb on the long arm of chromosome 11 across a balanced translocation associated with schizophrenia. Genomics. 1995;28:420–428
- . A haplotype-based study of lithium responding patients with bipolar affective disorder on the Faroe Islands. Psychiatr. Genet. 1999;9:23–34
- . Genome scan of European–American schizophrenia pedigrees: results of the NIMH Genetics Initiative and Millennium Consortium. Am. J. Med. Genet. 1998;81:290–295
- . CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locus. Nat. Genet. 2001;28:335–343
- . DNA methylation and the mechanisms of CDKN2A inactivation in transitional cell carcinoma of the urinary bladder. Lab. Invest. 2000;80:1513–1522
- . Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22–q23. Nat. Genet. 1996;12:436–441
- A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22). Am. J. Med. Genet. 1996;67:40–45
- . BRE: a modulator of TNF-alpha action. FASEB J. 1998;12:1101–1108
- . Genes for schizophrenia? Recent findings and their pathophysiological implications. Lancet. 2003;361(9355):417–419
- . Gene-expression profiles in hereditary breast cancer. N. Engl. J. Med. 2001;344:539–548
- . Exploring and explaining epigenetic effects. Trends Genet. 1997;13:293–295
- . Disease-specific alterations in frontal cortex brain proteins in schizophrenia, bipolar disorder, and major depressive disorder. The Stanley Neuropathology Consortium. Mol. Psychiatry. 2000;5:142–149
- . Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat. Genet. 1998;19:187–191
- . Possible association between schizophrenia and a CAG repeat polymorphism in the spinocerebellar ataxia type 1 (SCA1) gene on human chromosome 6p23. Psychiatr. Genet. 1999;9:7–11
- . Hypomethylation of L1 LINE sequences prevailing in human urothelial carcinoma. Cancer Res. 1996;56:5698–5703
- . Retroviral RNA identified in the cerebrospinal fluids and brains of individuals with schizophrenia. Proc. Natl. Acad. Sci. U. S. A. 2001;98:4634–4639
- . The dopamine D3 receptor interacts with itself and the truncated D3 splice variant d3nf: D3–D3nf interaction causes mislocalization of D3 receptors. Mol. Pharmacol. 2000;58:677–683
- . A genome survey indicates a possible susceptibility locus for bipolar disorder on chromosome 22. Proc. Natl. Acad. Sci. U. S. A. 2001;98:585–590
- . Clinical features of schizophrenia and linkage to chromosomes 5q, 6p, 8p, and 10p in the Irish Study of High-Density Schizophrenia Families. Am. J. Psychiatry. 2000;157:402–408
- . The postsynaptic density at glutamatergic synapses. Trends Neurosci. 1997;20:264–268
- . Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat. Genet. 1995;11:241–247
- . Increased levels of expression of an NMDARI splice variant in the superior temporal gyrus in schizophrenia. NeuroReport. 2000;11:983–986
- . Leukemia inhibitory factor (LIF) mRNA-expressing neuronal subpopulations in adult rat basal forebrain. Neurosci. Lett. 1997;229:69–71
- . Identification of a brain- and reproductive-organs-specific gene responsive to DNA damage and retinoic acid. Biochem. Biophys. Res. Commun. 1995;206:764–774
- . Differential stress induction of individual Alu loci: implications for transcription and retrotransposition. Gene. 2001;276:135–141
- . K562 cells implicate increased chromatin accessibility in Alu transcriptional activation. Nucleic Acids Res. 2000;28:3031–3039
-
.
Genome imprinting regulated by the mouse Polycomb group protein Eed.
Nat. Genet. 2003;
- . Anticipation in schizophrenia: a review and reconsideration. Am. J. Med. Genet. 1999;88:686–693
- . Perinatal risk factors and schizophrenia: selective review and methodological concerns. Epidemiol. Rev. 1995;17:107–112
- . Undermethylation of Alu sequences in ICF syndrome: molecular and in situ analysis. Cytogenet. Cell Genet. 1997;77:308–313
- . Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse. Trends Neurosci. 2001;24:479–486
- . Potential linkage disequilibrium between schizophrenia and locus D22S278 on the long arm of chromosome 22. Am. J. Med. Genet. 1995;60:465–467
- . Leukemia inhibitory factor inhibits neuronal terminal differentiation through STAT3 activation. Proc. Natl. Acad. Sci. U. S. A. 2002;99:9015–9020
- . Cell and tissue requirements for the gene eed during mouse gastrulation and organogenesis. Genesis. 2001;31:142–146
- . No evidence of increased risk for schizophrenia or bipolar affective disorder in persons with aneuploidies of the sex chromosomes. Psychol. Med. 2001;31:425–430
- . Molecular genetics of schizophrenia. Clin. Exp. Pharmacol. Physiol. 2001;28:66–69
- . Evidence for linkage by transmission disequilibrium test analysis of a chromosome 22 microsatellite marker D22S278 and bipolar disorder in a Palestinian Arab population. Am. J. Med. Genet. 2000;96:836–838
- . Linkage of a composite inhibitory phenotype to a chromosome 22q locus in eight Utah families. Am. J. Med. Genet. 1999;88:544–550
- . Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature. 1998;393:386–389
- . Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation. Mol. Cell Biol. 2001;21:6406–6417
- . A YAC contig encompassing the 11q14.3 breakpoint of a translocation associated with schizophrenia, and including the tyrosinase gene. Mamm. Genome. 1999;10:649–652
- . The genes for major psychosis: aberrant sequence or regulation?. Neuropsychopharmacology. 2000;23:1–12
- . Human morbid genetics revisited: relevance of epigenetics. Trends Genet. 2001;17:142–146
- . Schizophrenia: an epigenetic puzzle?. Schizophr. Bull. 1999;25:639–655
- . Psychiatric epigenetics: a new focus for the new century. Mol. Psychiatry. 2000;5:342–346
- Sequential strategy to identify a susceptibility gene for schizophrenia: report of potential linkage on chromosome 22q12–q13.1: Part 1. Am. J. Med. Genet. 1994;54:36–43
- . Metastable epialleles in mammals. Trends Genet. 2002;18:348–351
- . Epigenetic control of gene expression. Results Probl. Cell Differ. 1999;25:189–204
- . Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 1, 6, 8, 10, and 12. Am. J. Med. Genet. 1997;74:247–253
-
.
Methylation dynamics, epigenetic fidelity and X chromosome structure.
In:
Wolffe A editors. Epigenetics.
Novartis Foundation Symposium. vol. 214:Chistester: Wiley; 1998;p. 214–227
-
.
DNA methylation in health and disease.
Nat. Rev., Genet. 2000;1:11–19
- . Alu repeated DNAs are differentially methylated in primate germ cells. Nucleic Acids Res. 1994;22:5121–5127
- . Effects of oncostatin M on human cerebral endothelial cells and expression in inflammatory brain lesions. J. Neuropathol. Exp. Neurol. 2001;60:1087–1098
- . A transmission disequilibrium and linkage analysis of D22S278 marker alleles in 574 families: further support for a susceptibility locus for schizophrenia at 22q12. Schizophr. Res. 1998;32:115–121
- . Aiolos and Ikaros: regulators of lymphocyte development, homeostasis and lymphoproliferation. Apoptosis. 2002;7:277–284
- Evaluation of a susceptibility gene for schizophrenia on chromosome 6p by multipoint affected sib-pair linkage analysis. Nat. Genet. 1995;11:325–327
- Potential linkage for schizophrenia on chromosome 22q12–q13: a replication study. Am. J. Med. Genet. 1995;60:436–443
- . Further evidence for a susceptibility locus on chromosome 10p14–p11 in 72 families with schizophrenia by nonparametric linkage analysis. Am. J. Med. Genet. 1998;81:302–307
- . Changes in pre-mRNA splicing factors during neural differentiation in P19 embryonal carcinoma cells. Int. J. Biochem. Cell. Biol. 1999;31:1279–1287
- . DNA methylation represses transcription in vivo. Nat. Genet. 1999;22:203–206
- . Alu RNA transcripts in human embryonal carcinoma cells. Model of post-transcriptional selection of master sequences. J. Mol. Biol. 1992;226:689–706
- . Association of calcium/calmodulin-dependent kinase II with developmentally regulated splice variants of the postsynaptic density protein densin-180. J. Biol. Chem. 2000;275:25061–25064
- . Support for a possible schizophrenia vulnerability locus in region 5q22–31 in Irish families. Mol. Psychiatry. 1997;2:148–155
- . A schizophrenia locus may be located in region 10p15–p11. Am. J. Med. Genet. 1998;81:296–301
- . Schizophrenia after prenatal famine. Further evidence. Arch. Gen. Psychiatry. 1996;53:25–31
-
.
Genes, environment and schizophrenia.
Br. J. Psychiatry. 2001;40:s18–s24
Suppl.
- . Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system. J. Neurochem. 1999;72:1707–1716
- . Report of the chromosome 18 workshop. Am. J. Med. Genet. 1999;88:263–270
- . Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation. Nat. Genet. 1999;23:474–478
- . Obstetric complications and age at onset in schizophrenia: an international collaborative meta-analysis of individual patient data. Am. J. Psychiatry. 1997;154:1220–1227
- . Genetic refinement and physical mapping of a chromosome 18q candidate region for bipolar disorder. Eur. J. Hum. Genet. 1999;7:427–434
- . Evidence of linkage disequilibrium between schizophrenia and the SCa1 CAG repeat on chromosome 6p23. Am. J. Hum. Genet. 1996;59:731–736
- . Cytosine methylation and the ecology of intragenomic parasites. Trends Genet. 1997;13:335–340
PII: S0920-9964(03)00278-0
doi: 10.1016/j.schres.2003.09.004
© 2003 Elsevier B.V. All rights reserved.
« Previous
Next »
Schizophrenia Research
Volume 67, Issue 1
, Pages 95-106
, 1 March 2004
