Schizophrenia Research
Volume 67, Issue 1 , Pages 107-109 , 1 March 2004

Family-based association study of the functional monoamine oxidase A gene promoter polymorphism and schizophrenia

  • Jin-Bo Fan
  • ,
  • Mao-Sheng Yang
  • ,
  • Jun-Xia Tang
  • ,
  • Lin He

      Affiliations

    • Corresponding Author InformationCorresponding author. Bio-X Life Science Research Center, Shanghai Jiao Tong University, P.O. Box 501, Hao Ran Building, 1954 Hua Shan Road, Shanghai 200030, PR China. Tel./fax: +86-21-62822491.

Received 28 May 2003

References 

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  2. DeLisi LE, Devoto M, Lofthouse R, Poulter M, Smith A, Shields G, et al. Search for linkage to schizophrenia on the X and Y chromosomes. Am. J. Med. Genet. 1994;54:113–121
  3. Jonsson EG, Morton N, Forslund K, Mattila-Evenden M, Rylander G, Asberg M, et al. Association between a promoter variant in the monoamine oxidase A gene and schizophrenia. Schizophr. Res. 2003;61:31–37
  4. Kunugi H, Ishida S, Kato T, Tatsumi M, Sakai T, Hattori M, et al. A functional polymorphism in the promoter region of Monoamine oxidase-A gene and mood disorders. Mol. Psychiatry. 1999;4:393–395
  5. Murphy DL, Wyatt RJ. Reduced monoamine oxidase activity in blood platelets from schizophrenic patients. Nature. 1972;238:225–226
  6. Norton N, Kirov G, Zammit S, Jones G, Jones S, Owen R, et al. Schizophrenia and functional polymorphisms in the MAOA and COMT genes: no evidence for association or epistasis. Am. J. Med. Genet. 2002;114:491–496
  7. Sabol SZ, Hu S, Hamer D. A functional polymorphism in the monoamine oxidase A gene promoter. Hum. Genet. 1998;103:273–279
  8. Sham PC, Curtis D. An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Ann. Hum. Genet. 1995;59:323–336
  9. Syagailo YV, Stober G, Grassle M, Reimer E, Knapp M, Jungkunz G, et al. Association analysis of the functional monoamine oxidase A gene promoter polymorphism in psychiatric disorders. Am. J. Med. Genet. 2001;105:168–171

PII: S0920-9964(03)00263-9

doi: 10.1016/j.schres.2003.08.004

Schizophrenia Research
Volume 67, Issue 1 , Pages 107-109 , 1 March 2004