Schizophrenia Research
Volume 69, Issue 1 , Pages 67-73 , 1 July 2004

Neurocognition and long-term prediction of quality of life in outpatients with severe and persistent mental illness

  • Daryl E. Fujii

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +1-808-236-8493; fax: +1-808-247-7335.
    • Department of Psychology, Hawaii State Hospital, 45-710 Keaahala Road, Kaneohe, HI 96744, USA
  • ,
  • A.Michael Wylie

      Affiliations

    • Department of Psychology, University of Hawaii, 2430 Campus Road, Honolulu, HI 96822, USA
  • ,
  • Jeffrey H. Nathan

      Affiliations

    • Department of Psychology, University of Hawaii, 2430 Campus Road, Honolulu, HI 96822, USA

Received 29 October 2002 ,Revised 26 March 2003 ,Accepted 30 March 2003.

References 

  1. Addington J, Addington D. Neurocognitive and social functioning in schizophrenia: a 2.5 year follow-up study. Schizophr. Res. 2000;44:47–56
  2. Bilder RM, Goldman RS, Volavka J, et al.  Neurocognitive effects of clozapine, olanzapine, risperidone, and haloperidol in patients with schizophrenia or schizoaffective disorder. Am. J. Psychiatry. 2002;159:1018–1028
  3. Bow-Thomas CC, Velligan DI, Miller AL, Olsen J. Predicting quality of life from symptomatology in schizophrenia at exacerbation and stabilization. Psychiatry Res. 1999;86:131–142
  4. Brekke JS, Kohrt B, Green MF. Neurospychological functioning as a moderator of the relationship between psychosocial functioning and the subjective experience of self and life in schizophrenia. Schizophr. Bull. 2001;27:697–708
  5. Brier A, Schrieber JL, Dyer J, et al.  National Institutes of Mental Health longitudinal study of chronic schizophrenia: prognosis and predictors of outcome. Arch. Gen. Psychiatry. 1991;48:239–246
  6. Butzlaff RL, Hooley JM. Expressed emotion and psychiatric relapse. Arch. Gen. Psychiatry. 1998;55:547–552
  7. Cohen CI, Talavera N. Functional impairment in older schizophrenia persons: towards a conceptual model. Am. J. Geriatr. Psychiatry. 2000;8:237–244
  8. Dickerson FB, Ringer NB, Parente F. Subjective quality of life in out-patients with schizophrenia: clinical and utilization correlates. Acta Psychiatr. Scand. 1998;98:124–127
  9. Fujii DE, Wylie AM. Neurocognition and community outcome in schizophrenia: long-term predictive validity. Schizophr. Res. 2002;59:219–223
  10. Fujii DE, Ahmed I, Jokumsen M, Compton JM. The effects of clozapine on cognitive functioning in treatment-resistant schizophrenic patients. J. Neuropsychiatry, Clin. Neurosci. 1997;9:240–245
  11. Gold JM, Goldberg RW, McNary SW, et al.  Cognitive correlates of job tenure among patients with severe mental illness. Am. J. Psychiatry. 2002;159:1395–1402
  12. Goldstein G, Allen DN, Seaton BE. A comparison of clustering solutions for cognitive heterogeneity in schizophrenia. J. Int. Neuropsychol. Soc. 1998;4:353–362
  13. Green MF, Kern RS, Braff DL. Neurocognitive deficits and functional outcome in schizophrenia: are we measuring the right stuff?. Schizophr. Bull. 2000;26:119–136
  14. Halford WK, Schweitzer RD, Varghese FN. Effects of family environments on negative symptoms and quality of life of psychotic patients. Hosp. Community Psychiatry. 1991;42:1241–1247
  15. Halstead WC. Brain and Intelligence. Chicago: University of Chicago Press; 1947;
  16. Hansson L, Middelboe T, Merinder L, et al.  Predictors of subjective quality of life in schizophrenia patients living in the community. A Nordic multicentre study. Int. J. Soc. Psychiatry. 1999;45:247–258
  17. Harvey PD, Keefe RSE. Studies of cognitive change in patients with schizophrenia following novel antipsychotic treatment. Am. J. Psychiatry. 2001;158:176–184
  18. Helsegrave RJ, Awad AG, Voruganti LN. The influence of neurocognitive deficits and symptoms on quality of life in schizophrenia. J. Psychiatry Neurosci. 1997;22:235–243
  19. Ho BC, Nopoulous P, Flaum M, et al.  Two-year outcome in first-episode schizophrenia: predictive value of symptoms for quality of life. Am. J. Psychiatry. 1998;155:1196–1201
  20. Huppert JD, Smith TS. Longitudinal analysis of subjective quality of life in schizophrenia: anxiety as the best symptom predictor. J. of Nerv. Ment. Dis. 2001;189:669–675
  21. Ingraham LJ, Aiken CB. An empirical approach to determining criteria for abnormality in test batteries with multiple measures. Neuropsychology. 1996;10:120–124
  22. Kasckow JW, Twamley E, Mulchahey JJ, et al.  Health-related quality of well-being in chronically hospitalized patients with schizophrenia: comparison with matched outpatients. Psychiatry Res. 2001;103:69–78
  23. Kurtz MM, Moberg PJ, Gur RC, Gur RE. Approaches to cognitive remediation of neuropsychological deficits in schizophrenia: a review and meta-analysis. Neuropsychol. Rev. 2001;11:197–210
  24. Lehman AF. A quality of life interview for the chronically mentally ill. Eval. Program Plann. 1988;11:51–62
  25. Lehman AF, Postrado LT, Rachuba LT. Convergent validation of quality of life assessment for persons with severe mental illness. Qual. Life Res. 1993;2:327–333
  26. Lehman A, Kernan E, Postrado L. In: Toolkit for Evaluating Quality of Life for Persons with Severe Mental Illness. Baltimore, MD: University of Maryland School of Medicine; 1995;p. 72–92
  27. McCabe R, Roder-Wanner UU, Hoffman K, Priebe S. Therapeutic relationships and quality of life: association of two subjective constructs in schizophrenia patients. Int. J. Soc. Psychiatry. 1999;45:276–283
  28. Norman RMG, Malla AK, Voruganti LPN, et al.  The relationship of symptoms and level of functioning in schizophrenia to general wellbeing and the quality of life scale. Acta Psychiatr. Scand. 2000;102:303–309
  29. Paul GL, Lentz RJ. Psychosocial Treatment of Chronic Mental Patients: Milieu vs. Social Learning Programs. Cambridge: Harvard Univ. Press; 1977;
  30. Penades R, Boget T, Lomena F, et al.  Could the hypofrontality pattern in schizophrenia be modified through neuropsychological rehabilitation?. Acta Psychiatr. Scand. 2002;105:202–208
  31. Priebe S, Roeder-Wanner UU, Kaiser W. Quality of life in first-admitted schizophrenia patients: a follow-up study. Psychol. Med. 2000;30:225–230
  32. Ritsner M, Ponizovsky A, Endicott J, et al.  The impact of side-effects of antipsychotic agents on life satisfaction of schizophrenia patients: a naturalistic study. Eur. Neuropsychopharmacol. 2002;12:31–38
  33. Smith TE, Hull JW, Goodman M, et al.  The relative influences of symptoms, insight, and neurocognition on social adjustment in schizophrenia and schizoaffective disorder. J. of Nerv. Ment. Dis. 1999;187:102–108
  34. Wechsler D. A standardized memory scale for clinical use. J. Psychol. 1945;19:87–95
  35. Wechsler D. Wechsler Adult Intelligence Scale. New York: The Psychological; 1955;
  36. Wechsler D. Wechsler Adult Intelligence Scale-Revised. San Antonio, TX: The Psychological; 1981;
  37. Wiersma D, Nienhuis FJ, Slooff CJ, Giel R. Natural course of schizophrenic disorders: a 15-year followup of a Dutch incidence cohort. Schizophr. Bull. 1998;24:75–85

PII: S0920-9964(03)00122-1

doi: 10.1016/S0920-9964(03)00122-1

Schizophrenia Research
Volume 69, Issue 1 , Pages 67-73 , 1 July 2004