Audio-visual integration in schizophrenia

Abstract 

Integration of information provided simultaneously by audition and vision was studied in a group of 18 schizophrenic patients. They were compared to a control group, consisting of 12 normal adults of comparable age and education. By administering two tasks, each focusing on one aspect of audio-visual integration, the study could differentiate between a spatial integration deficit and a speech-based integration deficit. Experiment 1 studied audio-visual interactions in the spatial localisation of sounds. Experiment 2 investigated integration of auditory and visual speech. The schizophrenic group performed as the control group on the sound localisation task, but in the audio-visual speech task, there was an impairment in lipreading as well as a smaller impact of lipreading on auditory speech information. Combined with findings about functional and neuro-anatomical specificity of intersensory integration, the data suggest that there is an integration deficit in the schizophrenic group that is related to the processing of phonetic information.

Keywords:  Schizophrenia, Cross-modal integration, Audio-visual perception, Ventriloquism, Speech processes