Schizophrenia Research
Volume 52, Issue 3 , Pages 161-165 , 1 December 2001

Association of ZNF74 gene genotypes with age-at-onset of schizophrenia

  • K. Takase

      Affiliations

    • Department of Medical Genetics, Institute of Basic Medical Sciences and Department of Pediatrics, Institute of Clinical Science, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan
    • ,
  • T. Ohtsuki

      Affiliations

    • Department of Medical Genetics, Institute of Basic Medical Sciences and Department of Pediatrics, Institute of Clinical Science, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan
    • ,
  • O. Migita

      Affiliations

    • Department of Medical Genetics, Institute of Basic Medical Sciences and Department of Pediatrics, Institute of Clinical Science, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan
    • ,
  • M. Toru

      Affiliations

    • Department of Neuropsychiatry, Tokyo Medical and Dental University, School of Medicine, Tokyo, 113-8510, Japan
    • ,
  • T. Inada

      Affiliations

    • National Institute of Mental Health, National Center of Neurology and Psychiatry, Ichikawa, 272-0827, Japan
    • ,
  • K. Yamakawa-Kobayashi

      Affiliations

    • Department of Medical Genetics, Institute of Basic Medical Sciences and Department of Pediatrics, Institute of Clinical Science, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan
    • ,
  • T. Arinami

      Affiliations

    • Department of Medical Genetics, Institute of Basic Medical Sciences and Department of Pediatrics, Institute of Clinical Science, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81-298-53-3352; fax: +81-298-53-3333

Received 21 October 2000 ,Accepted 4 December 2000.

References 

  1. Arinami T, Ohtsuki T, Takase K, Shimizu H, Yoshikawa T, Horigome H, et al. Screening for 22q11 deletions in a schizophrenia population. Schizophr. Res. 2001;52:167–170
  2. Aubry M, Demczuk S, Desmaze C, Aikem M, Aurias A, Julien JP, et al. Isolation of a zinc finger gene consistently deleted in DiGeorge syndrome. Hum. Mol. Genet. 1993;2:1583–1587
  3. Carlson C, Papolos D, Pandita RK, Faedda GL, Veit S, Goldberg R, et al. Molecular analysis of velo-cardio-facial syndrome patients with psychiatric disorders. Am. J. Hum. Genet. 1997;60:851–859
  4. Carlson C, Sirotkin H, Pandita R, Goldberg R, McKie J, Wadey R, et al. Molecular definition of 22q11 deletions in 151 velo-cardio-facial syndrome patients. Am. J. Hum. Genet. 1997;61:620–629
  5. Grondin B, Bazinet M, Aubry M. The KRAB zinc finger gene ZNF74 encodes an RNA-binding protein tightly associated with the nuclear matrix. J. Biol. Chem. 1996;271:15 458–15 467
  6. Grondin B, Cote F, Bazinet M, Vincent M, Aubry M. Direct interaction of the KRAB/Cys2-His2 zinc finger protein ZNF74 with a hyperphosphorylated form of the RNA polymerase II largest subunit. J. Biol. Chem. 1997;272:27 877–27 885
  7. Murphy KC, Jones LA, Owen MJ. High rates of schizophrenia in adults with velo-cardio-facial syndrome. Arch. Gen. Psychiatry. 1999;56:940–945
  8. Payre F, Buono P, Vanzo N, Vincent A. Two types of zinc fingers are required for dimerization of the serendipity delta transcriptional activator. Mol. Cell. Biol. 1997;17:3137–3145
  9. Rodgers KK, Bu Z, Fleming KG, Schatz DG, Engelman DM, Coleman JE. A zinc-binding domain involved in the dimerization of RAG1. J. Mol. Biol. 1996;260:70–84
  10. Shprintzen RJ, Goldberg R, Golding-Kushner KJ, Marion RW. Late-onset psychosis in the velo-cardio-facial syndrome. Am. J. Med. Genet. 1992;42:141–142

PII: S0920-9964(00)00191-2

Schizophrenia Research
Volume 52, Issue 3 , Pages 161-165 , 1 December 2001

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