Schizophrenia Research
Volume 47, Issue 1 , Pages 69-75 , 15 January 2001

Relationship of extrapyramidal symptoms to age at onset and drug treatment in middle-aged and elderly schizophrenic patients

  • T.N. Srinivasan

      Affiliations

    • Schizophrenia Research Foundation (India), R/7A, North Main Road, Anna Nagar West (Extension), Chennai 600101, India
    • Corresponding Author InformationCorresponding author. Fax: +91-44-6263971
  • ,
  • R. Thara

      Affiliations

    • Schizophrenia Research Foundation (India), R/7A, North Main Road, Anna Nagar West (Extension), Chennai 600101, India
  • ,
  • R. Padmavathi

      Affiliations

    • Schizophrenia Research Foundation (India), R/7A, North Main Road, Anna Nagar West (Extension), Chennai 600101, India
  • ,
  • R.G. McCreadie

      Affiliations

    • Department of Clinical Research, Crichton Royal Hospital, Dumfries DG1 4TG, UK

Received 25 September 1999 ,Accepted 7 January 2000.

References 

  1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM IIIR). third ed.. Washington, DC: American Psychiatric Association; 1987;
  2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM IV). fourth ed.. Washington, DC: American Psychiatric Association; 1994;
  3. Bloom JC, Jernigan T, Archibald S, Harris MJ, Jeste DV. Quantitative magnetic resonance imaging of the brain in late-life schizophrenia. Am. J. Psychiatry. 1995;152:447–449
  4. Caligiuri MP, Lohr JB, Jeste DV. Parkinsonism in neuroleptic-naı̈ve schizophrenic patients. Am. J. Psychiatry. 1993;150:1343–1348
  5. Castle DJ, Murray RM. The epidemiology of late-onset schizophrenia. Schizophr. Bull. 1993;19:691–700
  6. Egan MF, Apud J, Wyatt RJ. Treatment of tardive dyskinesia. Schizophr. Bull. 1993;19:303–315
  7. Fenton WS, Wyatt RJ, McGlashan TH. Risk factors for spontaneous dyskinesia in schizophrenia. Arch. Gen. Psychiatry. 1994;51:643–650
  8. Hafner H, Nowotny B. Epidemiology of early-onset schizophrenia. Eur. Arch. Psychiatry Clin. Neurosci. 1995;245:80–92
  9. Harris MJ, Jeste DV. Late onset schizophrenia: an overview. Schizophr. Bull. 1988;14:39–55
  10. Howard R, Castle DJ, Wessley S, Murray RM. A comparative study of 470 cases of early-onset and late-onset schizophrenia. Br. J. Psychiatry. 1993;163:352–357
  11. Jeste DV, Wyatt RD. Tardive dyskinesia. Schizophr. Bull. 1993;19:303–315
  12. Jeste DV, Rockwell E, Harris MJ, Lohr JB, Lacro J. Conventional vs newer antipsychotics in elderly patients. Int. J. Geriatr. Psychiatry. 1990;7:70–76
  13. Jeste DV, Harris MJ, Krull A, Kuck J, McAdams LA, Heaton R. Clinical and neuropsychological characteristics of patients with late-onset schizophrenia. Am. J. Psychiatry. 1995;152:722–730
  14. Kane JM, Woerner M, Weinhold P, Wegner J, Kinon B. Incidence of tardive dyskinesia: five-year data from a prospective study. Psychopharm. Bull. 1984;20:39–40
  15. Kane JM, Jeste DV, Barnes TRE, Casy DE, Cole JO, Davis JM, et al. Tardive Dyskinesia: a Task Force Report of the American Psychiatric Association. Washington, DC: American Psychiatric Association; 1992;
  16. Kay SR, Fiszbein S, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr. Bull. 1987;13:262–273
  17. Khot V, Wyatt RJ. Not all that moves is tardive dyskinesia. Am. J. Psychiatry. 1991;148:661–666
  18. Kraepelin E. Dementia Praecox and Paraphrenia, Edinburgh: E&S Livingstone; 1919;translated by R.M. Barclay
  19. McCreadie RG, Thara R, Kamath S, Padmavathy R, Latha S, Mathrubootham N, et al. Abnormal movements in never-medicated Indian patients with schizophrenia. Br. J. Psychiatry. 1996;168:221–226
  20. McCreadie RG, Latha S, Thara R, Padmavathi R, Ayankaran JR. Poor memory, negative symptoms and abnormal movements in never treated Indian patients with schizophrenia. Br. J. Psychiatry. 1997;171:360–363
  21. Morgenstern H, Glazer WM. Identifying risk factors for tardive dyskinesia among long-term outpatients maintained with neuroleptic medication. Arch. Gen. Psychiatry. 1993;50:723–733
  22. Norusis MJ. SPSS/PC Advanced Statistics. Version 5.0. Chicago: SPSS Inc; 1992;
  23. Owens DG, Johnstone EC, Frith CD. Spontaneous involuntary disorders of movement. Arch. Gen. Psychiatry. 1982;39:452–461
  24. Schooler NR, Kane JM. Research diagnoses for tardive dyskinesia. Arch. Gen. Psychiatry. 1982;39:486–487
  25. Sharma V, Srinivasa Murthy S, Kishore Kumar Agarwal M, Wilkinson G. Comparison of people with schizophrenia from Liverpool, England and Sakalwara–Bangalore. India. Int. J. Soc. Psychiatry. 1998;44:225–230
  26. Simpson GM, Angus JWS. A rating scale for extrapyramidal side effects. Acta. Psychiatr. Scand. 1970;212(supplementum):11–19
  27. US Department of Health, Education, and Welfare. Abnormal involuntary movement scale (AIMS). In:  Weiner WJ,  Lang AE editor. Behavioural Neurology of Mental Disorders Advances in Neurology. vol. 65:New York: Raven Press; 1995;
  28. Waddington JL, Youssef HA. The life time outcome and involuntary movements of schizophrenia never treated with neuroleptic drugs. Br. J. Psychiatry. 1990;156:106–108
  29. Yassa R, Nair NPV, Iskandon H, Schwartz G. Factors in the development of severe forms of tardive dyskinesia. Am. J. Psychiatry. 1990;147:1156–1163

PII: S0920-9964(00)00008-6

Schizophrenia Research
Volume 47, Issue 1 , Pages 69-75 , 15 January 2001