Current Issue January 2012, Vol. 134, No. 1

Issue Highlights

The at risk state and early illness

Altered age-related trajectories of amygdala-prefrontal circuitry in adolescents at clinical high risk for psychosis: A preliminary study
January 2012(Vol. 134 | No. 1 | Pages 1-9)
Dylan G. Gee, Katherine H. Karlsgodt, Theo G.M. van Erp, Carrie E. Bearden, Matthew D. Lieberman, Aysenil Belger, Diana O. Perkins, Doreen M. Olvet, Barbara A. Cornblatt, Todd Constable, Scott W. Woods, Jean Addington, Kristin S. Cadenhead, Thomas H. McGlashan, Larry J. Seidman, Ming T. Tsuang, Elaine F. Walker, Tyrone D. Cannon, on behalf of the NAPLS Consortium

Reduced prepulse inhibition as an early vulnerability marker of the psychosis prodrome in adolescence
January 2012(Vol. 134 | No. 1 | Pages 10-15)
Tim B. Ziermans, Patricia F. Schothorst, Mirjam Sprong, Maurice J.C.M. Magnée, Herman van Engeland, Chantal Kemner

Prolactin concentrations in newly diagnosed, antipsychotic-naïve patients with nonaffective psychosis
January 2012(Vol. 134 | No. 1 | Pages 16-19)
Clemente Garcia-Rizo, Emilio Fernandez-Egea, Cristina Oliveira, Azucena Justicia, Eduard Parellada, Miguel Bernardo, Brian Kirkpatrick

Prevalence of item level negative symptoms in first episode psychosis diagnoses
27 January 2012
John Lyne, Brian O'Donoghue, Elizabeth Owens, Laoise Renwick, Kevin Madigan, Anthony Kinsella, Mary Clarke, Niall Turner, Eadbhard O'Callaghan
Abstract: The relevance of negative symptoms across the diagnostic spectrum of the psychoses remains uncertain. The purpose of this study was to report on prevalence of item and subscale level negativ...
Genetic overlap between schizophrenia and bipolar disorder: A study with AKT1 gene variants and clinical phenotypes
25 January 2012
Félicien Karege, Alexandre Méary, Nader Perroud, Stéphane Jamain, Marion Leboyer, Eladia Ballmann, Raphael Fernandez, Alain Malafosse, Franck Schürhoff
Abstract: Introduction: A number of epidemiological and genetic studies suggests an overlap of Schizophrenia and Bipolar disorder across the traditional binary classification. AKT1 gene variants were ...
Automated classification of fMRI during cognitive control identifies more severely disorganized subjects with schizophrenia
25 January 2012
Jong H. Yoon, Danh V. Nguyen, Lindsey M. McVay, Paul Deramo, Michael J. Minzenberg, J. Daniel Ragland, Tara Niendham, Marjorie Solomon, Cameron S. Carter
Abstract: The establishment of a neurobiologically based nosological system is one of the ultimate goals of modern biological psychiatry research. Developments in neuroimaging and statistical/machine ...
Cognitive adaptation training combined with assertive community treatment: A randomised longitudinal trial
24 January 2012
Jens Peter Hansen, Birte Østergaard, Merete Nordentoft, Lise Hounsgaard
Abstract: Background: Cognitive adaptation training (CAT) targets the adaptive behaviour of patients with schizophrenia and has shown promising results regarding the social aspects of psychosocial tre...
Regional differences in expression of β-tubulin isoforms in schizophrenia
24 January 2012
Mark S. Moehle, Richard F. Luduena, Vahram Haroutunian, James H. Meador-Woodruff, Robert E. McCullumsmith
Abstract: A growing body of evidence suggests that abnormal elements of the cytoskeleton may be associated with the pathophysiology of schizophrenia. Isoforms of a major cytoskeleton protein, β-tubuli...

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Article Title	Author(s)	Type	Pages
Schizophrenia, “Just the Facts”: What we know in 2008: Part 1: Overview March 2008 (Vol. 100 \| No. 1 \| Pages 4-19) Abstract Full Text PDF (496 KB)	Rajiv Tandon, Matcheri S. Keshavan, Henry A. Nasrallah	Full-length article	4-19
A large-scale validation study of the Medication Adherence Rating Scale (MARS) March 2008 (Vol. 100 \| No. 1 \| Pages 53-59) Abstract Full Text PDF (151 KB)	Laura Fialko, Philippa A. Garety, Elizabeth Kuipers, Graham Dunn, Paul E. Bebbington, David Fowler, Daniel Freeman et al.	Full-length article	53-59
The Brief Adherence Rating Scale (BARS) validated against electronic monitoring in assessing the antipsychotic medication adherence of outpatients with schizophrenia and schizoaffective disorder March 2008 (Vol. 100 \| No. 1 \| Pages 60-69) Abstract Full Text PDF (240 KB)	Matthew J. Byerly, Paul A. Nakonezny, A. John Rush	Full-length article	60-69
World Psychiatric Association Pharmacopsychiatry Section statement on comparative effectiveness of antipsychotics in the treatment of schizophrenia March 2008 (Vol. 100 \| No. 1 \| Pages 20-38) Abstract Full Text PDF (707 KB)	Rajiv Tandon, R.H. Belmaker, Wagner F. Gattaz, Juan J. Lopez-Ibor, Ahmed Okasha, Bruce Singh, Dan J. Stein, Jean-Pierre Olie, W. Wolfang Fleischhacker, Hans-Juergen Moeller, for the Section of Pharmacopsychiatry, World Psychiatric Association et al.	Full-length article	20-38
A randomized controlled trial of cognitive behavioral therapy for individuals at clinical high risk of psychosis January 2011 (Vol. 125 \| No. 1 \| Pages 54-61) Abstract Full Text PDF (315 KB)	Jean Addington, Irvin Epstein, Lu Liu, Paul French, Katherine M. Boydell, Robert B. Zipursky et al.	Full-length article	54-61

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The mission of Schizophrenia International Research Society (SIRS) is to be a worldwide organization that aims to bring together researchers in schizophrenia and related disorders in order to:

Exchange the latest advances in research and facilitate the application of these findings to clinical practice.
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Promote educational programs to effectively disseminate new research findings related to schizophrenia, both in the scientific community and the lay public.
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Special Collection "Schizophrenia Just the Facts".

A Collection of State of the Art Original Research and Reviews, following up on the "Just the Facts" paper by Professor Richard J. Wyatt, published in Schizophrenia Research, 1988.

A series of Facts and Invited Commentaries published in Schizophrenia Research, and Selected Articles published in the Journal of Psychiatric Research and the Asian Journal of Psychiatry.

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About Schizophrenia Research

An international, multidisciplinary journal, Schizophrenia Research promotes rapid publication of new international research that contributes to the understanding of schizophrenic disorders. It is hoped that this journal will aid in bringing together previously separated biological, clinical and psychological research on this disorder, and stimulate the synthesis of these data into cohesive hypotheses.

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2012 Biennial Meeting
3rd Biennial Schizophrenia International Research Conference, 14 - 18 April 2012, Florence, Italy

Abstract submission for oral and poster presentation for the SIRS Biennial Meeting is 1 December, 2011.

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The Officers, Board of Directors and Program Committee invite you to participate in the 3rd Biennial Schizophrenia International Research Conference. Click here to visit the conference website with additional information. We hope you will participate in the 3rd Biennial Schizophrenia International Research Conference.